| Title | Venue | Year | Impact | Source |
| 4101 | HYDROXYCHLOROQUINE ATTENUATES HERG CHANNEL BY PROMOTING THE MEMBRANE CHANNEL DEGRADATION: EVIDENCES FOR QT-INTERVAL PROLONGATION IN COVID-19 PATIENTS WITH HYDROXYCHLOROQUINE TREATMENT | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4102 | VACCINE ASSOCIATED ATRIAL FIBRILLATION Background: Vaccines have been mainly described to provide cardioprotective effects with rare reports showing rare association with myopericarditis. However, vaccines have not been well-studied regarding their effects on heart rhythm disorders. Methods: We used the Food and Drug Administration (FDA) Vaccine Adverse Event Reporting System (VAERS) between 1990-2021 to search for atrial fibrillation and other less prevalent arrhythmias. Disproportionality signal analysis was conducted by measuring reporting odds ratio (ROR) with 95% confidence interval (CI). Results: Over 1,300,000 adverse events were reported between 1990-2021. Among these events, atrial fibrillation was reported 2149 times in association with various vaccines. 90% of atrial fibrillation was associated with COVID-19 vaccines with ROR of 9.7739 (CI: 8.3703 to 11.4130) (P<0.0001). Interestingly, influenza vaccines, polyvalent polysaccharide pneumococcal (PPSV23) vaccine, pneumococcal 13-valent (PCV13) vaccine, zoster vaccine, and tetanus-containing vaccines were significantly associated with reduced atrial fibrillation. Of note, deaths were predominantly within the 50-year-old and above age group. Conclusion: While vaccines have not been linked to heart rhythm disorders, the introduction of COVID-19 vaccines in 2020 showed a significant association with atrial fibrillation. This study showed an unprecedented detrimental effect of COVID-19 vaccines on atrial fibrillation and warrants the need to take that into consideration when prescribing COVID-19 vaccines. | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4103 | DID THE COVID-19 PANDEMIC CAUSE PATIENTS WITH TYPE I STEMI OR NSTEMI TO DELAY SEEKING MEDICAL ATTENTION? | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4104 | NOVEL CTEPH MIMICKERS IN THE COVID-19 ERA | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4105 | CARDIOVASCULAR IMPAIRMENT IN LONG COVID ONE YEAR POST-SARS-COV-2 INFECTION | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4106 | THE IMPACT OF COVID-19 ON CARDIOLOGY PRACTICE IN RURAL AREAS | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4107 | BRUGADA PHENOCOPY IN COVID-19 PATIENT WITH FEVER AND HYPERKALEMIA | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4108 | SIMULTANEOUS ARTERIAL AND VENOUS THROMBOSIS IN A HEALTHY MALE AFTER A MILD COVID-19 INFECTION | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4109 | MULTISYSTEM INFLAMMATORY SYNDROME IN ADULTS: AN EMERGING COMPLICATION OF COVID-19 | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4110 | RECOGNIZING AND MANAGING MYOCARDITIS FOLLOWING COVID-19 VACCINATION: MITIGATING RISK OF SUDDEN CARDIAC DEATH IN ATHLETES | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4111 | WHEN LESS IS MORE: PURULENT PERICARDITIS FOLLOWING COVID-19 PNEUMONIA | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4112 | THE ROLE OF TARGETED TEMPERATURE MANAGEMENT POST-VENTRICULAR FIBRILLATION IN THE COVID-19 POSITIVE PATIENT | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4113 | STEMI IN COVID-19: NOT ALWAYS A MIMIC! | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4114 | A NEAR-MISS: ACUTE CORONARY THROMBOSIS IN A YOUNG PATIENT WITH COVID-19 | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4115 | HIGHLIGHTING THE RISE OF VACCINE-ASSOCIATED MYOCARDITIS AND WHAT IT MEANS FOR THE FUTURE OF MRNA VACCINES Background: Vaccine-associated Myocarditis (VAM) is increasingly documented as a complication of COVID-19 mRNA vaccines. In the United States, as of 10/16/2021 188.9 million are fully vaccinated with mRNA vaccines. VAM has an incidence of 4.8 cases per million post 2nd dose of mRNA vaccines. We present a case of mRNA VAM in a young male and challenges faced in screening and management of this rare condition in a time where clearer guidelines are needed. Case: 45 y/o male with no PMH presented with acute onset sharp midsternal chest pain associated with dyspnea and diaphoresis. Patient received the 2nd dose of the Moderna vaccine three days prior. Initial EKG: ST-elevations in leads V2-V4;troponin 4.37 (peaked at 7.3);CRP 25.8. Coreg was initiated. Emergent cardiac catheterization: nonobstructive CAD, mildly reduced systolic function 50%. Subsequent echo: EF 40% with mild hypokinesis in apical segments. Colchicine was started. Symptoms resolved and patient was discharged with avoidance of strenuous activity. 1st follow-up: improved symptomatology. Lisinopril was added. Repeat echo: EF 60%. 2nd follow-up 2 weeks later: he had presyncope. Holter: no arrhythmia. Cardiac MRI: multifocal mid-myocardial and subepicardial late gadolinium enhancement in apical and basal segments consistent with myocarditis. After 2 months, the patient was asymptomatic and exercise tolerant. Decision-making: New data from the CDC, and the Israeli National Database indicate a causal relationship between the new mRNA vaccines and the increase in VAM. This complication predominantly affects young males like this patient within 7 days post 2nd dose. In this age group, observed numbers of VAM were > 10 times more than expected. This data incited a high index of suspicion which led to the diagnosis. Conclusion: Since this vaccine technology will likely monopolize future vaccine production, this condition is expected to increase in prevalence and the medical community needs to remain vigilant. Better guidance is needed on how best to screen and manage. Further research is thus warranted. We maintain that mRNA vaccines provide benefits which far outweigh this often self-limited complication. | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4116 | MASSIVE BIVENTRICULAR THROMBOSIS IN ASYMPTOMATIC CORONAVIRUS-2019 INFECTION | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4117 | A PRESENTATION OF DELAYED MYOCARDITIS AFTER CORONAVIRUS DISEASE-2019 | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4118 | INCESSANT PERICARDITIS AND CARDIAC TAMPONADE FOLLOWING THE BNT162B2 MRNA COVID-19 VACCINE | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4119 | FROM 13% TO 60%: A RARE CASE OF MULTISYSTEM INFLAMMATORY SYNDROME IN ADULTS 4 WEEKS FOLLOWING COVID-19 INFECTION | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4120 | THE USE OF VENO-ARTERIAL ECMO IN A COVID-19 PATIENT WITH CARDIOGENIC SHOCK: A LIFE WAS SAVED | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4121 | COVID-19 VACCINE INDUCED MYOCARDITIS IN TWO OLDER ADULTS WITH CARDIOVASCULAR RISK FACTORS | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4122 | COVID-19 PRESENTING WITH MYOCARDIAL INFARCTION | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4123 | TRANSESOPHAGEAL ECHOCARDIOGRAM GUIDED PULMONARY ARTERY CANNULATION FOR VENO-PULMONARY ARTERY EXTRACORPOREAL MEMBRANE OXYGENATION Background: Pulmonary arterial (PA) cannulation for veno-pulmonary artery extracorporeal membrane oxygenation (V-Pa ECMO) is a treatment for critically ill patients in respiratory and right ventricular (RV) failure. Conventional fluoroscopic guided PA cannulation does not provide direct visualization of the catheter, PA and pulmonic valve. Complications of sub-optimal catheter placement include PA perforation and inadequate hemodynamic support. The following case study uses transesophageal echocardiogram (TEE) and right heat catheterization to simultaneously assess hemodynamics and directly visualize PA catheter placement to optimize support. Case: A 28 year old male with COVID acute respiratory distress syndrome and multisystem organ failure was placed on venovenous ECMO. He subsequently developed RV dysfunction necessitating PA cannulation for RV support via V-Pa ECMO. Right heart catheterization demonstrated an elevated central venous pressure (CVP), normal pulmonary capillary wedge pressure (PCWP) and elevated CVP/PCWP ratio consistent with RV dysfunction. A Protek Duo catheter was placed with fluoroscopic and TEE guidance. Decision-making:. Conclusion: The TEE clearly demonstrated the outflow cannula was in the main PA and proximal to the PA bifurcation. Fenestrations were observed distal to the pulmonic valve and mechanical flow was observed at the distal tip of the catheter (figure 1). Pulsatile pulmonic regurgitation without mechanical regurgitation was also observed. [Formula presented] | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4124 | SYMPTOMATIC NON-SUSTAINED VENTRICULAR TACHYCARDIA ASSOCIATED WITH RESOLVED MILD COVID-19 | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4125 | WAVE J SYNDROME/EARLY REPOLARIZATION ASSOCIATED WITH COVID-19, CASE REPORT | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4126 | ACUTE MYOCARDITIS AFTER MRNA COVID-19 VACCINATION AND DIAGNOSIS AIDED WITH CARDIAC MAGNETIC RESONANCE FINDINGS CASE SERIES IN YOUNG PATIENTS | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4127 | EFFUSIVE CONSTRICTIVE PERICARDITIS RELATED TO COVID-19 | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4128 | NEW ATRIAL FIBRILLATION AND SYNCOPE IN A COLLEGIATE ATHLETE IMMEDIATELY FOLLOWING COVID-19 VACCINATION | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4129 | STEMI FOLLOWING MRNA COVID-19 VACCINATION | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4130 | A RARE CASE OF SINUS NODE DYSFUNCTION IN A PATIENT WITH SEVERE COVID-19 PNEUMONIA | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4131 | VENTRICULAR TACHYCARDIA RELATED TO COVID-19 VACCINE IN HEALTHY INDIVIDUAL | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4132 | CORONARY ARTERY PERFORATION AND TAMPONADE DUE TO PCI IN A PATIENT WITH STEMI DUE TO COVID-19: RESOLUTION OF THE COMPLICATION WITH COIL EMBOLIZATION AND AUTOTRANSFUSION | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4133 | REMDESIVIR induced EXTREME SINUS BRADYCARDIA IN COVID-19 | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4134 | ADULT-ONSET STILL'S DISEASE AND CARDIOMYOPATHY FOLLOWING COVID-19 INFECTION | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4135 | TWO BIRDS, ONE STONE: MANAGING MULTIPLE ARTERIAL THROMBOTIC EVENTS IN COVID-19 | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4136 | SELF-LIMITING MYOCARDITIS IN A YOUNG FEMALE: VIRUS OR VACCINE? Background: Although rare, there is increasing incidence of myocarditis in young adult males who receive the second dose of the COVID-19 mRNA vaccine. We present a rare case of myocarditis in a young female following the initial dose. Case: A 20-year-old female presented with progressive pleuritic chest pain and fever. Past medical history was significant for depression and COVID-19 infection 5 months prior to admission. She received the first dose of the Moderna mRNA vaccine one week prior to admission. She had elevated D-dimer, erythrocyte sedimentation rate (ESR), and troponin levels. Electrocardiogram showed PR depression. Echocardiogram, respiratory viral panels, and cultures were normal. Decision-making: Due to persistent worsening chest pain, she underwent cardiac magnetic resonance imaging (CMRI), which was consistent with myocarditis. She was treated with supportive care and her condition improved. Given the temporal relationship between vaccine administration and symptom onset, as well as negative viral testing, it was determined that the Moderna vaccine was likely the culprit. Conclusion: COVID-19 vaccine-induced myocarditis is becoming a more recognized entity, however other more common etiologies should be first ruled out. Nonetheless, the benefits of immunization against COVID-19 outweigh the risks of vaccine-induced myocarditis. [Formula presented] | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4137 | RE-EMERGENCE OF POST-MI COMPLICATIONS DURING THE COVID-19 PANDEMIC | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4138 | COVID CORONARY: INTRACORONARY THROMBOLYTICS TO THE RESCUE | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4139 | ELECTRICAL STORM IN A PATIENT WITH BRUGADA SYNDROME AND COVID-19 INFECTION | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4140 | SIMULTANEOUS ACUTE THROMBOTIC OCCLUSION INVOLVING THREE CORONARY ARTERIES. A UNIQUE ASSOCIATION WITH COVID-19 PNEUMONIA | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4141 | A CASE OF MYOPERICARDITIS IN A YOUNG ADULT MALE FOLLOWING MODERNA COVID-19 VACCINATION | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4142 | POST-OPERATIVE MANAGEMENT AFTER CARDIAC SURGICAL REVASCULARIZATION IN A COVID-19 POSITIVE PATIENT | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4143 | COVID-19 RELATED ARTERIAL THROMBOSIS SUCCESSFULLY TREATED WITH PERCUTANEOUS THROMBECTOMY | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4144 | THE PRESENCE OF INTRACARDIAC THROMBI IN MULTIPLE CHAMBERS: DID WE MISS COVID-19? | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4145 | COVID COAGULOPATHY ASSOCIATED AORTIC THROMBUS, PULMONARY EMBOLI, WITH RETROPERITONEAL HEMATOMA: A THERAPEUTIC DILEMMA | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4146 | MASSIVE CORONARY THROMBOSIS IN A YOUNG PATIENT WITH COVID-19 INFECTION. A CASE REPORT | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4147 | COVID-19 VACCINATION ASSOCIATED RIGHT VENTRICULAR OUTFLOW TRACT VENTRICULAR TACHYCARDIA IN A STRUCTURALLY NORMAL HEART | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4148 | SUSTAINED VENTRICULAR TACHYCARDIA AS AN INITIAL PRESENTATION OF COVID-19 RELATED PULMONARY EMBOLISM DESPITE PREVIOUS RIVAROXABAN THERAPY | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4149 | COVID HEART BREAK: DEVELOPING TAKOTSUBO STRESS CARDIOMYOPATHY DURING ACUTE CORONAVIRUS INFECTION | J Am Coll Cardiol | 2022 | | CORD-19 |
| 4150 | THE COVID ROLLERCOASTER: DYSAUTONOMIA IN A CRITICALLY ILL PATIENT | J Am Coll Cardiol | 2022 | | CORD-19 |
