| Title | Venue | Year | Impact | Source |
3351 | Fiscal Stabilization in the United States: Lessons for Monetary Unions The debate about the use of fiscal instruments for macroeconomic stabilization has regained prominence in the aftermath of the Great Recession, and its relevance has suddenly increased further, after the recent Covid-19 shock. The analysis of fiscal stabilization in the United States, a monetary union equipped with a common fiscal capacity, has often informed the literature on the European EMU and could serve as a reference for its possible future reforms. This paper expands that literature in three ways: first, by measuring stabilization not only as inter-state risk-sharing of asymmetric shocks, but also as intertemporal stabilization of common shocks; second, by doing this for specific items in the US federal budget, both on the revenue and on the expenditure side; and third, by also measuring the impact of the federal system of unemployment benefits and of its extension as a response to the Great Recession. Corporate and personal income tax, on the revenue side, and social security benefits and federal grants, on the spending side, are the most effective items. The US federal system of unemployment insurance provides great stabilization in the event of a large shock, in particular when enhanced by the discretionary program of extended benefits. These findings imply that a proper design of the budget can maximize its stabilization effect, when it helps bridging the gap between higher mobility of capital and lower mobility of labor, by collecting revenues based on the income of the most mobile factor (corporate income tax) and providing support to the income of the least mobile factor (social security). | N/A | 2022 | | CORD-19 |
3352 | Rethink International Intervention. Afghanistan, Mali and Now? The recent take-over of the Taliban regime in Afghanistan marks a turn in international crisis and conflict management. The configuration as a double-hatted mission to secure and rebuild on the one hand, and in countering insurgency and terrorism on the other finally failed, an outcome that seems to recur in Mali. International law of transition and whole-of-system approaches remain however hypercritical work on the ground. A successful flexible framework for sustainable conflict transformation and peace processes must absorb lessons of both autocratic realpolitik and a massive trend of bipolarisation of geopolitics. | N/A | 2022 | | CORD-19 |
3353 | Aus Corona für die Zukunft familienfördernder Angebote lernen: Eine Fokusgruppenstudie mit Eltern und Fachkräften BACKGROUND: The onset of the coronavirus pandemic created diverse stressors for families with small children such as isolation, limited public and private childcare options, and balancing work and childcare. Fear of the future, feelings of uncertainty and loneliness led to a rise in mental health problems. Public family support services also faced significant challenges: while families felt more need for support, established means of reaching families and providing services were severely curtailed. OBJECTIVES: The current study aimed at capturing pandemic-related changes in family needs and at documenting experiences in the use of newly developed analog and digital services provided by public family support institutions in the city of Hamburg, Germany. MATERIALS AND METHODS: We conducted focus groups with staff members of different types of public family support services and parents who were using these services. Central topics of discussion were pandemic-related experiences and ideas for the future of public family support services. RESULTS: Results confirm an increase in family pressures. Parents and staff members missed low-threshold accessibility of services and personal contact and dialogue. Creative approaches to complement services digitally were developed. Several of these approaches were considered beneficial, especially for reaching new target groups and strengthening interprofessional cooperation in the field. CONCLUSIONS: In-person support services need to be upheld. However, digital services can effectively complement analog formats. A successful combination requires effective resource distribution and staff member qualification measures. | N/A | 2022 | | CORD-19 |
3354 | The Role of Scientific Expertise in COVID-19 Policy-making: Evidence from Four European Countries Immense uncertainty and the need for drastic interventions cause politicians to rely heavily on scientific advice for underpinning or legitimating their COVID-19 decision-making. This paper explores the role of scientific advice in this policy field in Germany, Italy, the Netherlands and the UK. It shows that scientific advice is based on the disciplinary, mainly medical, backgrounds of advisors but is also influenced by social and economic values, which are core to what politicians find important. During the pandemic a growing gap between scientific advice and political decisions is observed. | N/A | 2022 | | CORD-19 |
3355 | Assessment of the biotechnological activity of wheat hydrolysates prepared with the Biarum bovei extract In this study, Biarum bovei extract was used to produce bioactive peptides from wheat gluten protein and the biological and functional properties of the hydrolysates were determinated. The results showed that Biarum bovei extract has its highest protease activity (7.3 U/mg protein) at 45 °C and pH 5. Based on electrophoresis analysis, the molecular weight of hydrolysate was < 10 kDa. F1 fraction had the highest antioxidant activity in DPPH (65.85 ± 2.64 µmol TE/g)) and ABTS radical scavenging assays (295.81 µmol TE/g). F2 fraction with 86.3 ± 0.48 had the ability to inhibit the ACE enzyme. The F3 and F1 fractions had statistically the highest inhibition rate (49.37 ± 0.12%. and 79.19 ± 1.13%) in alpha-glucosidase and alpha amylase, respectively. The F1, F2 fractions hydrolysate had an inhibitory effect on Escherichia coli, Staphylococcus aureus, Listeria monocytogenes and Bacillus cereus. Functional properties of hydrolysates with increasing molecular weight, increased significantly. The presence of high levels (p ≤ 0.05) of amino acids with hydroxyl groups, hydrophobic and positive charged in fractions had critical role on biological and technological activity. These findings confirmed the efficiency of gluten hydrolysates with low molecular weight (F1 < 3 kDa) on biofunctionality such as scavenging radical activity, ACE inhibitory, antidiabetic and antibacterial activity could be beneficial from health and technological perspectives. | N/A | 2022 | | CORD-19 |
3356 | Legal countermeasures against COVID-19 in Japan: effectiveness and limits of non-coercive measures This paper analyzes the Japanese legal responses to COVID-19. Japan did not declare the state of emergency on the constitutional level. In addition, it did not enact a new law and instead amended existing statutes several times to cope with the situation. The paper first introduces provisions of the Novel Influenza Act and Infectious Diseases Acts provisions before and after the February 2021 amendments. The remarkable feature of the Japanese countermeasures was the focus on non-coercive measures. There is no compulsory scheme to ensure “staying at home” for general residents. Regarding the facility managers, the NIA provided for the public announcement of non-compliance of the “recommendation” to ensure effectiveness. The legal nature of such public announcements is disputed in Japanese administrative law. The February 2021 amendments added the possibility of issuing an order whose effectiveness was guaranteed by administrative fines. This paper analyzes the traditional emphasis of “administrative guidance” in Japan and proposes hypotheses as to why open non-compliance cases of facility managers are observed. Concerning patients, prior to the February 2021 amendment, the IDA provided for the problematic legal figures of “recommendation” and “immediate execution”. The Feb. 2021 amendment, which added administrative fines, made the legal figure more complex. COVID-19 countermeasures have highlighted the difficulty of legal control when public behavior change is a policy goal. We must proceed by trial and error and accumulate knowledge regarding legal regulations or governmental messages that effectively affect public behavior. In the process, we should embrace the basic principles of constitutional democracy, such as the democratic legitimacy and accountability of government decisions and the principle of the rule of law. Simultaneously, we must remember that infectious disease control is a matter of human rights and discrimination, especially considering the unfortunate history of infectious disease control in Japan. | N/A | 2022 | | CORD-19 |
3357 | Gauging the effects of COVID-related changes to the medical student surgical clerkship experience: a mixed-methods study PURPOSE: This study sought to understand the medical student experience on the restructured surgical clerkship during the COVID-era to provide guidance for future scenarios affecting student participation in clinical activities. METHODS: Medical students completing an anonymous 70-question survey at the conclusion of their surgical clerkship from June 2019 to October 2020 were divided into 2 cohorts: students completing their clerkship prior to March 2020 and after June 2020. Quantitative assessment was performed to evaluate the clerkship performance and perceptions. Resulting findings were used to construct an interview guide and conduct semi-structured interviews. RESULTS: Fifty-nine medical students rotated through the surgical clerkship prior to COVID and 23 during the COVID-era. No differences in perception of the surgical clerkship, participation in essential activities, or shelf examination scores were found. Students completing their clerkship during the COVID-era reported a lower perception of interaction and professional relationships with attending and resident surgeons (p = 0.03). Qualitatively, students completing their clerkship during the COVID-era struggled to balance clinical experiences with personal wellness and noted that building relationships with faculty was substantially more difficult. CONCLUSIONS: There does not appear to be a difference in the level of participation in essential clerkship activities nor a diminished perception of learning between students completing their surgical clerkship before or during the pandemic. However, there does appear to be a difference in the relationships formed between students and attending surgeons. Altered didactic structures and apprenticeship-type rotations may help mitigate such effects. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s44186-022-00015-2. | N/A | 2022 | | CORD-19 |
3358 | Shadow banking contraction and innovation efficiency of tech-based SMEs-based on the implementation of China's New Asset Management Regulation Tech-based SMEs are important subjects for achieving national innovation-driven development, and it is crucial to study whether and how changes in the macro-institutional environment affect their innovation efficiency. New Asset Management Regulation (NAMR) is a policy promulgated by the Chinese government to address the chaotic expansion of shadow banking in China, and this study treats it as a quasi-natural experiment, selecting a sample of Chinese GEM-listed firms from 2015 to 2019, adopting the event study method and the generalized double difference method, and empirically testing the impact of shadow banking contraction on the innovation efficiency of Chinese tech-based SMEs and its mechanism. This study finds that shadow banking contraction under the NAMR significantly improves innovation efficiency of tech-based SMEs. The mechanism test finds that the NAMR can optimize the debt financing structure of tech-based SMEs, reduce their financing costs and financing risks, and ultimately accelerate their innovation efficiency by improving their financing efficiency, which supports the hypothesis of “financing efficiency view”; it is further found that, to tech-based SMEs, the more they rely on shadow banking and the severer financing constraints they endure, the more obvious NAMR’s effect is on improving innovation efficiency. The findings not only provide some empirical evidence to clarify the controversy of shadow banking in China from the perspective of firm innovation, but also have some implications for the subsequent financial regulatory reform. | N/A | 2022 | | CORD-19 |
3359 | Century Impact of Macromolecules for Advances of Sensing Sciences Impact of macro molecular theory on the progress of sensing sciences and technology has been presented in the light of materials developments, advances in physical and chemical properties. The chronological advances in the properties of macromolecules have significantly improved the sensing performances towards gases, heavy metals, biomolecules, hydrocarbon, and energetic compounds in terms of unexplored sensing parameters, durability, and working lifetime. In this review article, efforts have been made to correlate the advances in structure and interactivity of macro-molecules with their sensing behavior and working performances. The significant findings on the macromolecules towards advancing the sensing sciences are highlighted with the suitable illustration and schemes to establish it as a potential “microanalytical technique” along with existing challenges. GRAPHICAL ABSTRACT: [Image: see text] | N/A | 2022 | | CORD-19 |
3360 | Caracterización de las manifestaciones cutáneas por infección de SARS-COV-2 en pacientes de América Latina Introduction In 2019, the SARS-CoV-2 coronavirus emerged, producing COVID-19, which caused a pandemic that spread rapidly around the world; in severe cases, it can trigger cytokine storm syndrome and lead to death. Cutaneous manifestations can be associated with the expression of the ACE2 receptor in keratinocytes, these have been described in the literature from different countries. This review seeks to document the skin presentations that have been described in patients with COVID-19 in Latin America. Methodology. We researched in nine databases for articles in Spanish, Portuguese and English, until March 10, 2021, using the terms: “Skin”, “Cutaneous manifestations”, “COVID-19”, “SARS-COV-2”, associating them with Latin American countries. Basic data was obtained from the patients, then a table was created in Microsoft Excel to analyze and compare this data. Results 22 publications from nine countries were identified. We obtained information from 92 patients, predominantly female with an average age of 31.6 years. 99 dermatologic lesions were documented, in order of frequency: rash, wheals, petechiae-purpura and papules. In 70 patients the affected body segment was described, mainly the trunk, lower and upper limbs. We found 39 photographs and 5 histopathologies. The most indicated treatments were corticosteroids, antimalarials and recombinant interferon. Conclusions Differences can be observed in the description of cutaneous manifestations caused by COVID-19, between Latin American publications and the ones found in other countries. There seems to be a specific pattern with a predominance of erythematous rash with wheals, while pseudo-perniosis was less representative. | N/A | 2022 | | CORD-19 |
3361 | Ungeimpfte sind zu melden, aber nicht zwingend sofort freizustellen | N/A | 2022 | | CORD-19 |
3362 | Gesundheitsminister Lauterbach beantwortet Fragen aus den Praxen | N/A | 2022 | | CORD-19 |
3363 | Gesundheitspolitik | N/A | 2022 | | CORD-19 |
3364 | Ambulante Weiterbildung, Bedarfsplanung und Honorare im Fokus | N/A | 2022 | | CORD-19 |
3365 | Klare Positionierung gegen den Krieg in der Ukraine | N/A | 2022 | | CORD-19 |
3366 | TCTAP C-033 CHIP-Choice OR Only Option..!! For Complicated Post Covid Case With Severely Calcified LM Trifurcation Lesion | J Am Coll Cardiol | 2022 | | CORD-19 |
3367 | TCTAP C-101 Lost and Found | J Am Coll Cardiol | 2022 | | CORD-19 |
3368 | TCTAP C-012 Stormy Primary Percutaneous Coronary Intervention During COVID-19 Pandemic | J Am Coll Cardiol | 2022 | | CORD-19 |
3369 | TCTAP A-064 Impact of the COVID-19 Pandemic on Cardiology Services and Catheterization Volumes in the Second Year: A Comparison of 2020 and 2021 at a Tertiary Cardiac Centre in Bangladesh | J Am Coll Cardiol | 2022 | | CORD-19 |
3370 | TCTAP A-006 Characteristics and Outcomes in Patients Presenting With COVID-19 and ST-Segment Elevation Myocardial Infarction | J Am Coll Cardiol | 2022 | | CORD-19 |
3371 | TCTAP C-097 Coronary Perforation With a Twist | J Am Coll Cardiol | 2022 | | CORD-19 |
3372 | Exploring COVID-19 incidence hotspot in Metropolitan area of Pakistan using geo-statistical approach: a study of Lahore city Globally, COVID-19 is a top level public health concern. This paper is an attempt to identify and assess COVID-19 incidence hotspots in Metropolitan area of Pakistan using geo-statistical approach. The study is based on secondary data. The COVID-19 confirmed cases record (15/03/2020 to 15/04/2020) of entire Metropolitan area is obtained from hospitals and National Institute of Health website. Point-level geo-coding technique was applied on patient’s record and the relative location was converted into absolute location. Getis-Ord Gi* statistical model was applied in ArcGIS 10.3 to calculate Z-score and P values for each point location representing the COVID-19 incidence intensity. Then inverse distance weighted technique of spatial interpolation was applied on Z-score and spatial clusters of crime were geo-visualized in the form hotspot and cold spot. Spatially, more than 50% of land area of Allama Iqbal, Samanabad, Gulburg and Cantonment is covered by very high incidence zone which is surrounded by high incidence zone whereas Ravi, Shalimar, and north of Wagha and Aziz Bhatti towns are located in very low incidence zone. This study provides a suitable methodological framework for identification and analysis infectious disease hotspots. The study can also facilitate health and related authorities to fight war against COVID-19. Similarly, it can help policy makers to manage the movement of travelers and restrict social interaction. | N/A | 2022 | | CORD-19 |
3373 | Telemedicine and IPMN: Analysis of a new follow-up strategy during COVID-19 outbreak | Pancreatology | 2022 | | CORD-19 |
3374 | A bibliometric mapping of shadow education research: achievements, limitations and the future This study aims to map the literature on shadow education using metadata extracted from 488 publications indexed in the Web of Science database. It is termed as shadow education because much of its content mimics what is learned in schools. The study uses bibliometric procedures to describe and visually represent available literature on shadow education in terms of main sources, key authors, institutions, and countries leading the production and dissemination of research on shadow education. Further, the study elaborates on h-classics publications to obtain an in-depth understanding of the most influential scientific outputs in this domain. Key findings of the study are that research on shadow education (a) has experienced steady growth over the last decade; (b) is disseminated through a wide range of outlets, mainly in the disciplines of sociology of education, economics of education, educational psychology, and language education; (c) is published mainly by scholars working in East Asia and the United States; (d) has focused on tangible (quantifiable) benefits related to improved examination results; and (e) reveals how this form of instruction primarily benefits students hailing from high socioeconomic backgrounds, thereby contributing to greater educational inequality. This study also suggests pedagogical implications and areas for ongoing research. | N/A | 2022 | | CORD-19 |
3375 | Cotton Weaving Waste Incorporation in PVC Composites The largest amount of solid waste from the textile industries is mainly derived from fabric manufacturing until the cutting stage: hard fibers (spinning waste), beaming and soft fibers (weaving yarn waste), and off-cuts (cutting process). This research aimed to (i) conduct an exploratory interview with a large Brazilian cotton textile manufacturer to identify its main solid waste and corresponding destinations; and (ii) produce and evaluate PVC composites reinforced with cotton textile residues from the weaving process. Cotton fibrous reinforcements in the proportion of 2.5% (w/w) presented the best results of tensile strength and elongation concerning the others. Briquette residue (2.5%) had better dispersion in the matrix and slightly higher tensile strength when compared to other residues. The composites presented different visual aspects, and their use in fashion products with sustainable appeal could be a viable alternative. Therefore, additional tests should be performed to ensure the appropriate mechanical properties for applications in this and other areas. | N/A | 2022 | | CORD-19 |
3376 | Verpleegkundig leiderschap: hoe doe je dat? | N/A | 2022 | | CORD-19 |
3377 | RN2Blend: zenden én meebewegen | N/A | 2022 | | CORD-19 |
3378 | nieuws: Berichten uit de verpleegkundige praktijk | N/A | 2022 | | CORD-19 |
3379 | Hoofdredactioneel | N/A | 2022 | | CORD-19 |
3380 | Regelvrijheid is de sleutel tot efficiëntere zorg | N/A | 2022 | | CORD-19 |
3381 | Redactioneel | N/A | 2022 | | CORD-19 |
3382 | Deep recurrent Gaussian Nesterovs recommendation using multi-agent in social networks Due to increasing volume of big data the high volume of information in Social Network put a stop to users from acquiring serviceable information intelligently so many recommendation systems have emerged. Multi-agent Deep Learning gains rapid attraction, and the latest accomplishments address problems with real-world complexity. With big data precise recommendation has yet to be answered. In proposed work Deep Recurrent Gaussian Nesterov’s Optimal Gradient (DR-GNOG) that combines deep learning with a multi-agent scenario for optimal and precise recommendation. The DR-GNOG is split into three layers, an input layer, two hidden layers and an output layer. The tweets obtained from the users are provided to the input layer by the Tweet Accumulator Agent. Then, in the first hidden layer, Tweet Classifier Agent performs optimized and relevant tweet classification by means of Gaussian Nesterov’s Optimal Gradient model. In the second layer, a Deep Recurrent Predictive Recommendation model is designed to concentrate on the vanishing gradient issue arising due to updated tweets obtained from same user at different time instance. Finally, with the aid of hyperbolic activation function in the output layer, building block of the predictive recommendation is obtained. In the experimental study the proposed method is found better than existing GANCF and Bootstrapping method 13–21% in case of recommendation accuracy, 22–32% better in recommendation time and 15–22% better in recall rate. | N/A | 2022 | | CORD-19 |
3383 | Successful School Interventions for Students with Disability During Covid-19: Empirical Evidence from Australia Children and young people with disability are a “vulnerable” population within a pandemic context as they face structural inequities and discrimination as a result of their impairments. In this paper, we report research that sought to examine the learning experiences of children and young people with disability during the COVID-19 pandemic. We wanted to understand how this group fared and whether different interventions impacted on these experiences. Data were collected from an online survey organized by Children and Young People with Disability Australia (CYDA) that garnered responses from more than 700 families. The study contributes empirical evidence to the growing literature about COVID-19-related impacts on learners already recognized as experiencing multiple disadvantages in schooling. We find some significant gaps in supports offered to students with disability and their families. Notwithstanding that some students did not receive any support from their schools, where supports were offered, social supports had the greatest positive impact on feelings of learner engagement. Our findings support key propositions in the social and emotional learning literature, namely that particular resourcing should be dedicated to social interaction and feelings of belonging as these are crucial to learners engaging in learning processes. There are clear implications of these findings in terms of what educational institutions might do to help engage students with disability in remote learning. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s40299-022-00659-0. | N/A | 2022 | | CORD-19 |
3384 | Temporal variation analysis, impact of COVID-19 on air pollutant concentrations and forecasting of air pollutants over the cities of Bangalore and Delhi in India Indian cities are highly vulnerable to atmospheric pollution in recent years, due to exponential growth in urbanisation and industrialisation, and the increased pollution has been made to focus on the temporal variation analysis and forecasting of air pollutants over major Indian cities like Delhi and Bangalore. PM(2.5) concentrations are nearly 60.5% less than the annual average value during monsoon season while 76.3% more during the winter months. Ozone concentrations increase during the summer months (~ 46.3% more than the annual average) in Delhi, whereas in Bangalore, ozone concentrations are more (~ 75% more than the annual average) during the winter months. Variations of carbon monoxide and nitrogen oxides are significantly less comparatively. COVID-19 lockdown has a substantial positive impact on air pollution. Air pollutant concentrations are reduced during phase I and phase II of the lockdown. Pollutants, especially NOx and PM(2.5) concentrations, are drastically reduced compared to the previous years. NOx concentrations are reduced by ~ 20% in Bangalore, whereas ~ 50% in Delhi. PM(2.5) concentrations are reduced by ~ 41% in Delhi and ~ 55% in Bangalore. Forecasting of pollutants will be helpful in providing the valuable information for the optimal air pollution control strategies. It has been observed that linear model gives better results compared to ARIMA and Exponential Smoothening models. By forecasting, the concentration of NO(2) is 115.288 µg/m(3), the ozone is 30.636 µg/m(3), SO(2) is 11.798 µg/m(3), and CO is 2.758 mg/m(3) over Delhi in 2021. All the pollutants during forecasting showed a rising trend except sulphur dioxide. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s12517-022-09996-2. | N/A | 2022 | | CORD-19 |
3385 | Economic fundamentals, policy responses and state-level municipal bond sensitivity to COVID-19 prevalence This paper conducts a state-by-state analysis of the financial impact of the COVID-19 pandemic on the U.S. municipal bond market. Using panel regressions and state-by-state regressions, we find that the prevalence rates of the COVID-19 virus negatively impacted the aggregate performance of municipal bonds. The study also explored whether the disparities in the economic fundamentals of U.S. states, as well as the COVID-19 mitigation policies employed by each state, can explain the sensitivity of the state’s municipal bond to its COVID-19 prevalence rates. States with more desirable economic fundamentals and robust COVID-19 mitigation policies appeared to have higher COVID-19 sensitivities than states that do not. This finding may be due to a baseline effect, in which the higher levels of economic activities in these states also make them more susceptible to the deleterious effects of the stronger mitigation policies enacted by them. | N/A | 2022 | | CORD-19 |
3386 | Replies to critics I reply to my critics in this symposium on my book, The Epistemic Role of Consciousness (Oxford University Press, 2019). | N/A | 2022 | | CORD-19 |
3387 | ISJ meeting, Osaka, 16-19 September 2022 | Ichthyol Res | 2022 | | CORD-19 |
3388 | Synthesis of indole-based oxadiazoles and their interaction with bacterial peptidoglycan and SARS-CoV-2 main protease: In vitro, molecular docking and in silico ADME/Tox study In the present study, Indole-based-oxadiazole (1A-17A) compounds were successfully synthesized. The structures of all synthesized compounds were fully characterized by different sophisticated spectroscopic techniques such 1H NMR, 13C NMR, EI-MS and HREI-MS. Further, the synthesized compounds were explored to investigate their broad-spectrum antibacterial and antibiofilm potential against multidrug resistant Pseudomonas aeruginosa (MDR-PA) and methicillin resistant Staphylococcus aureus (MRSA). The compounds possessed a broad spectrum of antibacterial activity having MIC values of values 1-8 mg/ml against the tested microorganisms. Compound A6 and A7 shows maximum antibacterial activity against MDR-PA, whereas A6, A7 and A11 shows highest activity against MRSA. Furthermore, antibiofilm assay shows that A6, A7 and A11 showed maximum inhibition of biofilm formation and it was found that at 4 mg/ml; A6, A7 and A11 inhibit MRSA biofilm formation by 81.1, 77.5 and 75.9%, respectively; whereas in case of P. aeruginosa; A6 and A7 showed maximum biofilm inhibition and inhibit biofilm formation by 81.5 and 73.7%, respectively. Molecular docking study showed that compounds A6, A7, A8, A10, and A11 had high binding affinity to bacterial peptidoglycan, indicating their potential inhibitory activity against tested bacteria, whereas A6 and A11 were found to be the most effective inhibitors of SARS CoV-2 main protease (3CLpro), with a binding affinity of −7.78 kcal/mol. Furthermore, SwissADME and pkCSM-pharmacokinetics online tools was applied to calculate the ADME/Tox profile of the synthesized compounds and the toxicity of these chemicals was found to be low. The Lipinski, Veber, Ghose, and Consensus LogP criteria were also used to predict drug-likeness levels of the compounds. Our findings imply that the synthesized compounds could be a useful for the preventing and treating biofilm-related microbial infection as well as SARS-CoV2 infections. | N/A | 2022 | | CORD-19 |
3389 | Reprint of: Development of vaccines and vaccinal strategies against COVID-19: The information contributing to shared decision-making The public has many questions about COVID-19 vaccines. The informing of general practitioners and other vaccinators provides healthcare users with clear and reliable information conducive to shared decision-making. While they constitute a bulwark against widespread vaccine hesitancy, informative supports can be tainted by doubt if they are not backed up by solid arguments convincingly addressing the manifold questions and concerns of healthcare users. | N/A | 2022 | | CORD-19 |
3390 | Forthcoming Issues | Clin Geriatr Med | 2022 | | CORD-19 |
3391 | Urbanization effect on Hyderabad seismic station Seismographs record earthquakes and also record various types of noise, including anthropogenic noise. In the present study, we analyse the influence of the lockdown due to COVID-19 on the ground motion at CSIR-NGRI HYB Seismological Observatory, Hyderabad. We analyse the noise recorded a week before and after the implementation of lockdown by estimating the probability density function of seismic power spectral density and by constructing the daily spectrograms. We find that at low frequency (<1 Hz), where the noise is typically dominated by naturally occurring microseismic noise, a reduction of ~2 dB for secondary microseisms (7–3 s) and at higher frequency (1–10 Hz) a reduction of ~6 dB was observed during the lockdown period. The reduction in higher frequencies corresponding to anthropogenic noise sources led to improving the SNR (signal-to-noise ratio) by a factor of 2 which is the frequency bandwidth of the microearthquakes leading to the identification of microearthquakes with Ml around 3 from epicentral distances of 180 km. | N/A | 2022 | | CORD-19 |
3392 | Consider differentials before diagnosing COVID-19 associated polyradiculitis Evidence is accumulating that SARS-CoV-2 infections and SARS-CoV-2 vaccinations can induce Guillain-Barre syndrome (GBS). More than 400 GBS cases after SARS-CoV-2 infection respectively vaccination have been reported as per the end of 2021. GBS is usually diagnosed according to the Brighton criteria, but also the Besta criteria or Hadden criteria are applied. The diagnosis can be supported by MRI with contrast medium of the cranial or spinal nerves showing enhancing nerve roots. As GBS can be complicated by autonomic dysfunction such as pupillary abnormalities, salivatory dysfunction, reduced heart rate variability, bowel disturbance (constipation, diarrhea), urinary hesitancy, urinary retention, or impotence, it is crucial to investigate GBS patients for autonomic involvement. Before diagnosing GBS various differentials need to be excluded, including neuropathy as a side effect of the anti-SARS-CoV-2 medication, critical ill neuropathy in COVID-19 patients treated on the ICU, and compression neuropathy in COVID-19 patients requiring long-term ventilation. | Eur J Transl Myol | 2022 | | CORD-19 |
3393 | Preface for Brain Tumor Pathology vol. 39 issue 2: (Special issue for the 39th Annual Meeting of the Japan Society of Brain Tumor Pathology) | Brain Tumor Pathol | 2022 | | CORD-19 |
3394 | Consumer characteristics and e-grocery services: the primacy of the primary shopper The literature does not agree on the precise role of socio-demographic characteristics in the adoption of online grocery shopping. This methodological note reviews the literature and shows that the differences in empirical results can to a large extent be explained by the data that is used. In particular, what matters is whether or not the survey that is exploited was targeted at the household member primarily responsible for the grocery shopping. I show that studies that use a non-targeted survey erroneously find that women are keener to adopt e-grocery services, in that the gender gap is simply due to women’s role as homemakers. I also show that such studies tend to underestimate the impact of education and income. | N/A | 2022 | | CORD-19 |
3395 | Occupations in the European Labour Market During the COVID-19 Pandemic In order to capture the consequences of the COVID-19 pandemic on the labour market, several aspects need to be taken into account. First, containment measures put in place in member states at different times and with different levels of severity determined the interruption of several economic activities that were considered non-essential. Second, different occupations require varying degrees of physical proximity and social interaction to be carried out; this implies that they can be considered more or less teleworkable, and affected by different levels of epidemiological risk of contagion. This paper shows the labour market impact of the pandemic on different categories of workers in the EU. Occupations are distinguished by three main characteristics: whether they are critical or non-critical, their level of technical teleworkability and the level of social interaction required in the job. We show that the impact of the COVID-19 pandemic on the labour market has been heterogeneous across occupations and that all three dimensions are relevant to determine whether and to what extent the occupations were affected by the pandemic. | N/A | 2022 | | CORD-19 |
3396 | Why Did (Almost) No One See the Inflation Coming? To understand the possible trajectory of inflation in 2022 and beyond, it is helpful to understand why the United States and Europe had so much inflation in 2021. | N/A | 2022 | | CORD-19 |
3397 | The EU Without Russian Oil and Gas | N/A | 2022 | | CORD-19 |
3398 | Modern Monetary Theory: The Right Compass for Decision-Making In the November/December 2021 issue of Intereconomics, Françoise Drumetz and Christian Pfister examine Modern Monetary Theory (MMT) and approach it from the policy consequences that would follow. This paper is a reply to Drumetz and Pfister. It restates the core of MMT and offers some suggestions for central banks. Theories are explanations of what we see, and MMT describes money creation and destruction. Hence, MMT cannot be and is not a political manifesto. In contrast to most other theories of money, MMT is falsifiable in its core statements, which are based on a balance sheet approach to macroeconomics. Since many central banks already educate the public about the creation of modern money through bank lending, it would be most welcome if they would do the same for the creation of modern money through government spending. Here, MMT and central bankers can find common ground to move forward and leave the theory of loanable funds and that of the money multiplier behind. | N/A | 2022 | | CORD-19 |
3399 | The Inflation Surge of 2021-22: Scarcity of Goods and Commodities, Strong Labor Markets and Anchored Inflation Expectations The key to understanding the series of supply shocks that have hit inflation is the nature of the COVID-19 recession. | N/A | 2022 | | CORD-19 |
3400 | Dental students face wellbeing crisis | Br Dent J | 2022 | | CORD-19 |