\ BIP! Finder for COVID-19 - Impact-based ranking

BIP! Finder for COVID-19

This version of BIP! Finder aims to ease the exploration of COVID-19-related literature by enabling ranking articles based on various impact metrics.

Last Update: 18 - 01 - 2023 (628506 entries)

Provided impact measures:
Popularity: Citation-based measure reflecting the current impact.
Influence: Citation-based measure reflecting the total impact.
Reader Attention: The current number of Mendeley readers.
Social Media Attention: The number of recent tweets related to this article.
*More details on these impact measures can be found here.
Score interpretations:
Exceptional score (in top 0.01%).
Substantial score (in top 1%).
Average score (in bottom 99%).
Score not available.
Main data sources:
CORD-19 dataset(1) (list of papers)
LitCovid hub(2) (list of papers)
PMC & PubMed (citations)
Mendeley (number of readers)
COVID-19-TweetIDs(3) (tweets)

Use:  Impact  Relevance & Impact
TitleVenueYearImpactSource
1651Patient Experience Survey: Antepartum Care During the First and Second Waves of the COVID-19 Pandemic  

J Obstet Gynaecol Can2022       CORD-19
1652Detection of SARS-CoV-2 Contamination in the Operating Room and Birthing Room Setting: Risks to Attending Healthcare Workers  

J Obstet Gynaecol Can2022       CORD-19
1653Peripartum Outcomes Following COVID-19 Vaccination in Late Pregnancy: Findings from a Population-Based Retrospective Cohort Study in Ontario, Canada  

J Obstet Gynaecol Can2022       CORD-19
1654Standard Versus Extended Neoadjuvant Chemotherapy: A Canadian Tertiary Centre Cohort Study of Ovarian Cancer Care Amidst the COVID-19 Pandemic  

J Obstet Gynaecol Can2022       CORD-19
1655Hands-on Training in a Virtual World: Novel Simulation-based Virtual Training for Subdermal Contraceptive Implant Placement and Removal  

J Obstet Gynaecol Can2022       CORD-19
1656Universal SARS-CoV-2 Testing Among Obstetrical Patients (UNIVERSE-OB) in Ottawa, Canada  

J Obstet Gynaecol Can2022       CORD-19
1657The Ethics of Using Off-Label Medications to Treat COVID-19  

Ann Emerg Med2022       CORD-19
1658Ein bunter Strauß an originellen Ideen: Bewerbungen zum Innovationspreis zeigen großen Erfindungsgeist  

N/A2022       CORD-19
1659People + Companies  

N/A2022       CORD-19
1660Weniger Fälle, aber dickere Tumore: Beeinflusst Coronapandemie die Versorgung maligner Melanome?  

N/A2022       CORD-19
1661A bi-objective blood supply chain model under uncertain donation, demand, capacity and cost: a robust possibilistic-necessity approach  

This paper addresses a multi-objective blood supply chain network design, considering economic and environmental aspects. The objective of this model is to simultaneously minimize a blood supply chain operational cost and its logistical carbon footprint. In order to embed the uncertainty of transportation costs, blood demand, capacity of facilities and carbon emission, a novel robust possibilistic-necessity optimization used regarding a hybrid optimistic-pessimistic form. For solving our bi-objective model, three multi-objective decision making approaches including LP-metric, Goal-Programming and Torabi- Hassini methods are examined. These approaches are assessed and ranked with respect to several attributes using a statistical test and TOPSIS method. Our proposed model can accommodate a wide range of decision-makers’ viewpoints with the normalized objective weights, both at the operational or strategic level. The trade-offs between the cost and carbon emission for each method has been depicted in our analyses and a Pareto frontier is determined, using a real case study data of 21 cities in the North-West of Iran considering a 12-month implementation time window.

N/A2022       CORD-19
1662An Overview of Vehicular Emission Standards  

In India, the ambient air quality has been degrading from past few decades especially in urban areas. Vehicular emissions are amongst one of the major reasons for the deterioration of ambient air quality in such areas. This article is an effort to review the vehicular emission standards of the major countries (USA, Europe, Japan and Australia) and compare with Indian emission standards. However, there exists several differences in present emission standards followed by different countries. For instance, emission standards in USA are fuel neutral, while no separate weight categorization exists among light-duty vehicles (LDVs). In Europe, Japan, Australia and India, separate weight categorization and emission limits for both petrol and diesel vehicles are provided. It was observed that different driving test cycles used by different countries are the reasons for numerical differences in vehicular emission standards. To rectify this, a worldwide harmonized test cycle (WHTC) is introduced by United Nations Economic Committee for Europe (UNECE) that would represent real-world driving and verifies that the statutory emission limits are not exceeded during actual driving. Countries like Japan and Europe have already been following the WHTC, while some other countries may introduce the same in near future. Yet the real-world emissions across the world keeps on diverging. In such situation, harmonization of vehicle emission standards worldwide is a bit challenging, based on dynamics of road conditions, driving patterns, environmental conditions, etc. Thus, more concerted research is needed for evolution of a common universal emission standards implementable worldwide so that the uniformity in information and policies available to the common public could be maintained.

N/A2022       CORD-19
1663Anguish and fears about attitude towards Covid-19 vaccines: contrasts between yes and no vax  

The present research investigates the possible causes of resistance to vaccination against the COVID-19 virus. A significant percentage of different countries' populations is refractory to being vaccinated (i.e., in October 2021, in Italy, 20% aged 40–50 years old). A 92-item questionnaire was filled in by a sample of 613 subjects, of which 50.4% said they were against COVID-19 vaccines (63.1% female). Guided by the hypothesis that emotionality constitutes a basis of pre-reflective judgment, items relating to fear, anger and anguish were introduced in the survey. The subjects compiled the Difficulties in Emotional Regulation Scale. The differences between the means of the two samples evaluated with the Student test show that it is, above all, the underlying anguish that constitutes the primary discriminant between the two samples. No Vax mainly considers external the sources of anguish, while Yes Vax sources of anguish appear more internal. From this result an interpretation is advanced: it seems more difficult for No Vax to trust authority recommendations/obligations to get vaccinated because anguish is located just outside the one's body, where Authority dominates. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s44202-022-00038-2.

N/A2022       CORD-19
1664Parameters that Motivate Table Olive Farmers To Buy Agricultural Insurance: The Case of Western Turkey  

Defining components that affect agricultural insurance contract decisions is indispensable to the sustainability of table olive cultivation in the region. The Akhisar district is located within the borders of Manisa province, a region in Turkey in which traditional, and the most famous, table olive varieties are grown. This study explores parameters that predict the decisions of farmers in this district to purchase agricultural insurance and identifies perceptions of agricultural insurance in the region. A survey was conducted among 121 purposefully selected farmers. Some farmers’ sociodemographic characteristics and their households were identified using basic descriptive statistics, such as arithmetic means and percentage rates, and factors that affect farmers’ decisions to buy agricultural insurance were defined using binary logistic regression. Although table olive farmers could insure their products against risk by buying full hail and frost packages within the scope of crop insurance, the desired success with agricultural insurance has not been achieved. Although the agricultural insurance that covers farmers who grow table olives remains insufficient, it still plays a role in patterns of agricultural production in the region, results in greater income than other agricultural products, and contributes to the government’s premiums for agricultural insurance. Future studies should expand insurance practices to improve farmers’ perceptions of agricultural insurance, especially regarding drought yield insurance for perennial fruit trees, including table olives.

N/A2022       CORD-19
1665Enter the Prince of Denmark: Entrepreneurship for a Resilient and Sustainable Economy  

N/A2022       CORD-19
1666Implementing Converged Security Risk Management: Drivers, Barriers and Facilitators  

Converged security risk management is an approach that addresses interdependencies between security-related business functions that have traditionally been managed by separate departments within organizations. It is a more effective means of addressing organizational security risks and threats than tackling physical and information security challenges separately, given that the boundaries between the two are frequently blurred. However, fully converged security remains the exception rather than the rule, leaving organizations increasingly vulnerable as their adoption and reliance on digital technologies accelerates. Through interviews with eight senior security professionals, this research identified key factors critical to effective converged security risk management, expressed as ‘drivers,’ ‘barriers,’ and ‘facilitators.’ The practitioners’ accounts illuminated how the modern threat landscape continues to drive further the need for such an approach, while the traditional separation of corporate security departments from the information security function in organizations remains a barrier. A greater focus on training and education, as well as soft skills, were identified as key priorities in the drive for an effective converged approach.

N/A2022       CORD-19
1667Establishing multi-perspective instruments in early education during COVID-19: measuring the implementation of protective measures and the subjective level of information about pandemic-related regulations  

This article describes the context, development, objectives, and content of three instruments. They stem from two questionnaires, used in the ERiK-Surveys 2020 and the Corona-KiTa-Study (CKS), two multi-perspective surveys which were developed by the German Youth Institute, to measure quality as well as challenges and solutions of the Corona pandemic in early childhood education and care (ECEC). The three instruments focus on (1) childcare center directors’ subjective level of information about pandemic-related regulations in the ERiK questionnaire and the extent of implementation of (2) hygiene and (3) protective measures in ECEC in the CKS questionnaire. First analyses suggest good performance and quality of the instruments. Further analyses (e.g., regarding validity and reliability) will be carried out. The instruments seem to be promising for future research, for example regarding medical questions in the field of ECEC. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s42409-022-00033-2.

N/A2022       CORD-19
1668Board diversity and financial statement comparability: evidence from China  

We investigate the relationship between board diversity (relation-oriented diversity, task-oriented diversity, and overall board diversity) and financial statement comparability. We find that diverse boards are positively associated with financial statement comparability, suggesting that board diversity improves governance mechanisms by alleviating agency conflicts, leading to higher comparability than homogenous boards. We also find that institutional ownership positively affects the association between board diversity and financial statement comparability. Furthermore, the positive effect of diversity, institutional ownership, and comparability are more pronounced in non-state-owned firms and non-crisis periods. Our findings remain consistent with a battery of econometric techniques and measures of comparability. This study provides new insights regarding the role of boardroom diversity in shaping the qualitative aspect of financial reporting, i.e., financial statement comparability. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s40821-022-00214-3.

N/A2022       CORD-19
1669Fast zwei Jahre Coronapandemie aus der Perspektive von Krebsbetroffenen  

N/A2022       CORD-19
1670What does neighbourhood climate action look like? A scoping literature review  

Cities are recognized as an important scale for framing and implementing plans and policies for action on climate change. Within the structure of cities, it is in urban neighbourhoods that climate action becomes tangible and has the potential to engage communities. Despite its importance, scholarly literature has played limited attention to the scale of the neighbourhood as a site for locating climate action. The objective of our paper is to provide an overview of the role of neighbourhoods in leading bottom-up climate action and its implications for urban planning based on a qualitative scoping review. Our findings indicate that neighbourhoods are conceptualized as a physically bounded scale for climate action as well as a web of social networks and relationships enabling this action. Neighbourhood climate action aims to achieve neighbourhood scale sustainability and resilience by engaging with residents, municipalities, local academic institutions, neighbourhood associations and non-governmental agencies. Scholars engage with a wide range of concepts like place-based attachment and social mobilization as well as established practice-oriented tools in defining and measuring neighbourhood climate action. However, the neighbourhood scale struggles with limited resources and power in creating sustained climate action as well as in engaging with and addressing socio-economically marginalized communities.

N/A2022       CORD-19
1671The welfare state in really hard times: Political trust and satisfaction with the German healthcare system during the COVID-19 pandemic  

The COVID-19 pandemic represents an enormous challenge for healthcare systems around the globe. Using original panel survey data for the case of Germany, this article studies how specific trust in the healthcare system to cope with this crisis has evolved during the course of the pandemic and whether this specific form of trust is associated with general political trust. The article finds strong evidence for a positive and robust association between generalized political trust and performance perceptions regarding the efficiency and fairness of the crisis response as well as individual treatment conditions. The article also shows that specific trust in healthcare remained relatively stable throughout 2020, but declined significantly in the spring of 2021.

J Eur Soc Policy2022       CORD-19
1672How do International Olympic Sport Federations innovate? the use of crowdfunding and the impact of COVID-19  

The purpose of this study was to contribute to the understanding of innovation and crowdfunding of International Olympic Sport Federations (IFs), which are the world governing bodies of their respective sports. Three research questions were addressed: the perceptions of the IFs on the implementation of their innovation programmes during the last four years (2016–2020), the impact of COVID-19 on the IFs capability to innovate, and the crowdfunding strategies of the IFs. A mixed method combining qualitative and quantitative approaches was used. An online semi-structured questionnaire which included an open answer section was completed by IFs executives (n = 22) and an analysis of the information provided by IFs through various content sources was conducted. Results showed that IFs with less funding had a significantly more innovative approach that their counterparts, that the perception of the impact of COVID-19 on the innovative capability was not unanimous, that they identified sport-specific programmes as the most innovative of all initiatives delivered during the pandemic, and that crowdfunding projects were implemented in their sport but mostly at individual and local levels. From a research perspective, since this is the first study that investigates the innovation and crowdfunding strategies of IFs, future directions include the need for further research with national and regional federations on these topics. Practical implications are suggested for IFs to deliver innovative programmes to satisfy their stakeholder needs and to consider new funding methods such as crowdfunding as part of their strategies.

Int J Sports Sci Coach2022       CORD-19
1673The Impact of COVID-19 on Reconstructive Surgery for Burns and Complex Wounds  

Plast Surg (Oakv)2022       CORD-19
1674Recycling and circular economy-towards a closed loop for metals in emerging clean technologies  

Resource efficiency, energy, and mobility transition are crucial strategies to mitigate climate change. The focus is on reducing the consumption of resources, especially energy and raw materials. While raw materials are the basis of our material world, their excessive consumption over the last decades has also contributed significantly to climate change. However, raw materials, and here especially metals, play a key enabling role as well for climate protection technologies, such as electro mobility, the hydrogen economy, and solar and wind power plants, and also for digitalization. Accordingly, it is necessary to make the use of raw materials much more resource-efficient than before and to use them as purposefully as possible instead of consuming them. Advanced circular economy systems and sophisticated recycling technologies build the backbone for the development of a resource efficient and sustainable society. Closed metal cycles contribute for a paramount share to this by securing relevant parts of the raw material supply for high-tech products and by reducing CO(2) emissions in their production at the same time. Interacting steps in multistage treatment processes by mechanical, chemical, and thermal unit operations are challenging but will give a competitive advantage for networks of industry and science that are able to handle that.

N/A2022       CORD-19
1675Die Erde unter den Füßen: Pädagogische Ideen für eine bedrückende Zeit  

Der Beitrag beschreibt die alternative Gestaltung einer Vorlesung während der Pandemie: statt aus dem Homeoffice lässt Kiaras Gharabaghi, der Autor, seine Veranstaltung an unterschiedlichen „lebendigen“ Orten in der Natur stattfinden. Dieses Format sei bei den Studierenden gut angekommen.

N/A2022       CORD-19
1676Preserving identities in post-industrial Rust Belt cities: reconsidering Buffalo's material memory  

In the context of post-industrial Rust Belt cities, much needed investment seldom makes room for proper debate on the material memory and place identity embodied in the rich industrial legacy. However, a reflection on the intrinsic value of the vacant industrial structures of these cities leads to the unveiling of their most authentic identity. This identity is directly related to the material experience of their structures as it speaks to the qualities of a lasting presence in the collective memory. Post-industrial structures display material conditions that define their place character, constituting a negotiation between ruin and construction. This text contends that post-industrial materiality embodies necessary and strategic connections between past heritage and future interventions, implying the possibility of cyclical renovation in a context of reinforced identity. The text focuses on the potential of the existing post-industrial legacy of the city of Buffalo, NY, arguing that the material dimension that once defined its productive infrastructure frames the potential consolidation of its physical memory and future identity, and as such, a consolidation of its future growth.

N/A2022       CORD-19
1677'The filthy people': Racism in digital spaces during Covid-19 in the context of South-South migration  

Notions of ‘race’ and disease are deeply imbricated across the globe. This article explores the historical, complex entanglements between ‘race’, disease, and dirtiness in the multicultural Chilean context of Covid-19. We conducted a quantitative content analysis and a discourse analysis of online readers’ comments (n = 1233) in a digital news platform surrounding a controversial news event to examine Chileans’ cultural representations of Haitian migrants and explore online racism and anti-immigrant discourse. Drawing on a decolonial approach, we argue that Covid-19 as a crisis has been fabricated at the expense of a constructed ‘other’. We show how colonial racist logics not only endure in digital spaces, but are made viral in new ways by representing Haitian migrants as ‘filthy’ and ‘disease carriers’. We identified two contemporary forms of racism – online cultural racism and online aggressive racism – through which people construct imaginaries of racial superiority in digital spaces.

N/A2022       CORD-19
1678The role of industry 4.0 technologies in overcoming pandemic challenges for the manufacturing sector  

Industry 4.0 aims to revolutionize the manufacturing sector to achieve sustainable and efficient production. The novel coronavirus pandemic has brought many challenges in different industries globally. Shortage in supply of raw material, changes in product demand, and factories closures due to general lockdown are all examples of such challenges. The adaption of Industry 4.0 technologies can address these challenges and prevent their recurrence in case of another pandemic outbreak in future. A prominent advantage of Industry 4.0 technologies is their capability of building resilient and flexible systems that are responsive to exceptional circumstances such as unpredictable market demand, supply chain interruptions, and manpower shortage which can be crucial at times of pandemics. This work focuses on discussing how different Industry 4.0 technologies such as Cyber Physical Systems, Additive Manufacturing, and Internet of Things can help the manufacturing sector overcome pandemics challenges. The role of Industry 4.0 technologies in raw material provenance identification and counterfeit prevention, collaboration and business continuity, agility and decentralization of manufacturing, crisis simulation, elimination of single point of failure risk, and other factors is discussed. Moreover, a self-assessment readiness model has been developed to help manufacturing firms determine their readiness level for implementing different Industry 4.0 technologies.

Concurr Eng Res Appl2022       CORD-19
1679Book Review: The Unequal Pandemic Covid-19 and Health Inequalities by Clare Bambra, Julia Lynch and Katherine E. Smith  

Eur J Soc Secur2022       CORD-19
1680Videoconferencing-based cognitive behavioral therapy for youth with anxiety and depression during COVID-19 pandemic  

The need for psychosocial intervention programmes to address the negative consequences of the COVID-19 pandemic and its associated lockdown restrictions on the mental health of young people is evident. Using a within subject pretest-posttest design, this study aimed to evaluate the effects of online Cognitive Behavioural Therapy (CBT)-based anxiety and depression management psychoeducation programmes on mental health and coping skills in youth ages 14–20. The Demographic Information Form, Revised Child Anxiety Depression Scale, and KidCope were administered before and after the psychoeducational programme to assess programme outcomes. The results indicate significant decreases in levels of anxiety, significant decreases in avoidance of anxiety-provoking situations and significant increases in coping skills following the online CBT Anxiety Management Psychoeducation Program. A significant decrease in depression scores was noted among the online CBT Depression Management Psychoeducation Program participants. Although these results should be interpreted cautiously due to limitations of the study (e.g., no control group, high attrition), they suggest that psychological prevention or intervention programmes may be beneficial for young people who are physically unable to go to school or who cannot interact face-to-face with social support networks.

Sch Psychol Int2022       CORD-19
1681Feasibility of Self-Guided Online Cognitive Behavioral Therapy for University Students During COVID-19  

Objective: This study aimed to test the feasibility and efficacy of a self-guided online cognitive behaviour therapy (iCBT) for university students in Hong Kong during COVID-19. Method: One group pre-post-test design with convenient sampling was adopted in this study, involving 84 university students who received a newly developed iCBT within an 8 week intervention period. The iCBT offered eight online modules for students to learn the skills of CBT at home through an online platform which was accessible any time anywhere anonymously with technical support only. Standardized assessment tools were used for outcomes assessment at the pre- and post-intervention periods. Results: Three quarters of participants completed all iCBT modules. The results of paired t-tests showed that, after completing the iCBT, participants showed reduction in anxiety, depression, and perceived stress. Conclusion: This study provides preliminary evidences to support the feasibility and efficacy of the self-guided iCBT for university students during COVID-19.

Res Soc Work Pract2022       CORD-19
1682Prevention and control of COVID-19 transmission in the indoor environment  

Indoor Built Environ2022       CORD-19
1683Elucidating the role of environmental management of forests, air quality, solid waste and wastewater on the dissemination of SARS-CoV-2  

The increasing frequency of zoonotic diseases is amongst several catastrophic repercussions of inadequate environmental management. Emergence, prevalence, and lethality of zoonotic diseases is intrinsically linked to environmental management which are currently at a destructive level globally. The effects of these links are complicated and interdependent, creating an urgent need of elucidating the role of environmental mismanagement to improve our resilience to future pandemics. This review focused on the pertinent role of forests, outdoor air, indoor air, solid waste and wastewater management in COVID-19 dissemination to analyze the opportunities prevailing to control infectious diseases considering relevant data from previous disease outbreaks. Global forest management is currently detrimental and hotspots of forest fragmentation have demonstrated to result in zoonotic disease emergences. Deforestation is reported to increase susceptibility to COVID-19 due to wildfire induced pollution and loss of forest ecosystem services. Detection of SARS-CoV-2 like viruses in multiple animal species also point to the impacts of biodiversity loss and forest fragmentation in relation to COVID-19. Available literature on air quality and COVID-19 have provided insights into the potential of air pollutants acting as plausible virus carrier and aggravating immune responses and expression of ACE2 receptors. SARS-CoV-2 is detected in outdoor air, indoor air, solid waste, wastewater and shown to prevail on solid surfaces and aerosols for prolonged hours. Furthermore, lack of protection measures and safe disposal options in waste management are evoking concerns especially in underdeveloped countries due to high infectivity of SARS-CoV-2. Inadequate legal framework and non-adherence to environmental regulations were observed to aggravate the postulated risks and vulnerability to future waves of pandemics. Our understanding underlines the urgent need to reinforce the fragile status of global environmental management systems through the development of strict legislative frameworks and enforcement by providing institutional, financial and technical supports.

N/A2022       CORD-19
16843058-SARS-COV-2 BINDING IN HEMATOPOIETIC STEM AND PROGENITOR CELLS UNDER LOW OXYGEN CONDITIONS  

The SARS-CoV-2 pandemic highlighted a need for in-depth understanding of interaction/identification of receptors and mechanisms/functional consequences of viral binding/entry. SARS-CoV-2 spike protein (SBP) facilitates viral entry via ACE2 and/or NRP1 binding, with DPP4 as a potential co-receptor. These binding partners are expressed on various cell types including hematopoietic stem and progenitor (HSC/HSPC) cells [1-3]. HSC/HSPCs generate blood cells and reside in the low oxygen (lowO2, 1-4%) bone marrow niches that provide critical signals for maintenance, self-renewal, and differentiation. To investigate aspects of SARS-CoV-2 interactions with HSC/HSPC such as endogenous receptor expression, SPB binding and subsequent functional alterations in native low O2, we performed transcriptional and phenotypic/functional analysis. In lowO2, we identified increased surface expression of ACE2, DPP4 and NRP1, and enhanced binding of SBP to HSC/HSPC populations which amplified proliferation of SBP bound in lowO2. ACE2 and DPP4 surface expression were ∼2-fold higher in HSPCs (p=0.017, p=0.001) and HSCs (p=0.010, p=0.03), and NRP1 was ∼1.5-fold (p=0.002) higher in HSPCs in lowO2 compared to air. Interestingly, in lowO2, overall SBP binding was enhanced in HSPC (2.2-fold, p<.001) and HSC (2.6-fold, p=.018). Although not all cells expressing ACE2/DPP4/NRP1 bind SBP (∼50%), all cells exhibiting SBP binding in HSC/HSPC populations are triple positive for ACE2, NRP1, and DPP4. Additionally, we observed greater than a 2-fold increase in proliferation of SBP bound vs unbound cells in replating assays in lowO2 (p<.001). These data impart compelling evidence that SBP binding/functional outcomes are unique in low O2, providing a foundation that may have potential clinical implications for COVID19 treatment and expanding our baseline understanding of SARS-CoV-2 viral binding implications.

Exp Hematol2022       CORD-19
1685Abstract #1170550: Changes in glycemic control and body weight over the course of the COVID-19 pandemic in an outpatient setting  

Endocr Pract2022       CORD-19
16863095-IMMUNE THROMBOCYTOPENIA AND BONE MARROW HEMOPHAGOCYTOSIS ASSOCIATED WITH SARS COV-2  

The clinical presentation of patients infected with SARS-CoV-2 is remarkably diverse. Likewise, the underlying pathophysiological mechanisms are proving complex. Disturbances in the blood coagulation system and cytokine storm, such as seen in hemophagocytic syndrome, are among the most serious ones. We present the case of a female 79-year-old patient with marked thrombocytopenia of 4 (150-450) x10^9/L occurring in the context of a confirmed SARS-CoV-2 infection. Clinically, one episode of epistaxis and petechiae was observed, otherwise no signs of bleeding occurred. Diagnostic workup included microscopic blood smear analysis, bone marrow cytologic evaluation and flow cytometric immunophenotyping. Hematological malignancies, thrombotic microangiopathies and common infections were excluded as cause of the low platelet count. In the bone marrow, cytology, the megakaryocytic lineage presented normocellular. However, several large hemophagocytes with engulfed hematopoietic cells were detected. A further evaluation of markers frequently associated with hemophagocytic syndrome was performed. Ferritin was 2888 (0-150) ng/mL, CRP and GOT were slightly elevated. The white blood count was normal with a marked decrease of lymphocytes to 0.13 (1.10-3.60) × 10^9/L. There was no fever or organomegaly and the patient was in good clinical constitution. Thus, we did not diagnose hemophagocytic syndrome. Due to no other explanation for the clinical and laboratory findings, the patient was diagnosed with immune thrombocytopenia and concomitant bone marrow hemophagocytosis associated to SARS-CoV-2. The first-line treatment consisting of prednisolone and intravenous immunoglobulins failed to induce an increase in the platelet count. As second-line treatment therapy with Eltrombopag, a TPO-agonist, was started and a sustainable response with platelets in the normal range was achieved.

Exp Hematol2022       CORD-19
1687Abstract #1185076: Poor Outcomes of Hospitalized COVID-19 Patients with Type 2 Diabetes and Chronic Kidney Disease  

Endocr Pract2022       CORD-19
1688Abstract #1184694: Premix Analog Insulin regimen is a Pragmatic approach in patients with T2DM with Mild to Moderate COVID-19 managed through Teleconsultations  

Endocr Pract2022       CORD-19
1689Abstract #1185162: Association of the prognostic biomarkers for COVID-19 with grade of Hyperglycemia in T2DM with Mild to Moderate COVID-19 managed through Teleconsultations- A Two Center Cohort Study  

Endocr Pract2022       CORD-19
1690Abstract #1176428: Thyroiditis: A Potential Complication of COVID-19 Infection  

Endocr Pract2022       CORD-19
1691Abstract #1184564: A 59-year-old man with type 2 diabetes mellitus with severe neuropsychiatric manifestations due to COVID-19 infection  

Endocr Pract2022       CORD-19
1692Abstract #1185166: Is hyperglycemia a risk factor associated with death in COVID patients everywhere in the world? Report from Honduras, Central America  

Endocr Pract2022       CORD-19
1693Abstract #1185190: New Onset Autoimmune Diabetes Associated with Acute SARS-COV-2 Infection  

Endocr Pract2022       CORD-19
1694Abstract #1168947: Thyroid bed lymphadenopathy after COVID-19 vaccine in a patient with history of thyroidectectomy due to Hurtle cell thyroid cancer  

Endocr Pract2022       CORD-19
1695Abstract #1184636: A Patient with Thyroid Storm Precipitated by COVID-19 Vaccine  

Endocr Pract2022       CORD-19
1696Abstract #1176119: Development of New Onset, Protracted Hyperglycemia Triggered by COVID-19 Vaccination with Ultimate Resolution in an Individual without Prior Dysglycemia  

Endocr Pract2022       CORD-19
1697Abstract #1153925: Dexamethasone Use and Insulin Requirements in Coronavirus Disease-19 Infection  

Endocr Pract2022       CORD-19
1698Abstract #1161413: Adrenal crisis in elderly patients with adrenal insufficiency following COVID-19 vaccination  

Endocr Pract2022       CORD-19
1699Abstract #1185161: Thyroiditis Related to mRNA-Based SARS-CoV-2 Vaccination: A Case Series  

Endocr Pract2022       CORD-19
1700Abstract #1183829: COVID-19 Outcomes and Mortality in Patients with Metabolic Syndrome in a County-Based Hospital Setting in a Primarily Hispanic Population  

Endocr Pract2022       CORD-19

(1) COVID-19 Open Research Dataset (CORD-19). 2020. Version 2022-06-02. Retrieved from https://ai2-semanticscholar-cord-19.s3-us-west-2.amazonaws.com/historical_releases.html. Accessed 2022-06-05. doi:10.5281/zenodo.3715506
(2) Chen Q, Allot A, & Lu Z. (2020) Keep up with the latest coronavirus research, Nature 579:193 and Chen Q, Allot A, Lu Z. LitCovid: an open database of COVID-19 literature. Nucleic Acids Research. 2020. (version 2023-01-10)
(3) Currently tweets of June 23rd to June 29th 2022 have been considered.

This service is provided "as is", without any warranties of any kind.