| Title | Venue | Year | Impact | Source |
| 1551 | Implementing COVID-19 scale-up registry protocol in national multiple sclerosis registry system of Iran Background: The national multiple sclerosis (MS) registry is aimed at monitoring and improving quality of care and providing feedback to improve health outcomes by systematic recording of data. In 2018, the nationwide MS registry of Iran (NMSRI) was initiated for collecting epidemiological data and information on health care provision for patients with MS. The aim of the current study was to introduce the role of implementing coronavirus disease 2019 (COVID-19) scale-up registry protocol in NMSRI and arrange the national MS generality with information obtained during the COVID-19 pandemic. Methods: The NMSRI group set up a program with crucial elements to collect the data of patients with MS who developed COVID-19. All MS cases with confirmed diagnosis of COVID-19 were enrolled in this study. New elements were considered to be added into the dataset, including demographic characteristics, definite diagnosis of COVID-19 and its symptoms, history of comorbidities, history of medications and hospitalization, changes in magnetic resonance imaging (MRI), and infection outcomes. Results: The COVID-19 data collection program was designed in NMSRI to collect data of MS cases with COVID-19 infection. The data collection protocol was explained to neurologists through an online training workshop. To the date of the study, 21 centers from 17 provinces of Iran were involved in the COVID-19 databases promoting NMSRI and 612 participants were registered successfully. Conclusion: We extended an agreement on data collection and developed it in NMSRI with various contributors to discover a critical need for COVID-19 awareness and monitor clinical training in MS. | Curr J Neurol | 2021 | | CORD-19 |
| 1552 | Délirium postopératoire, COVID-19 et analyses bayésiennes | N/A | 2022 | | CORD-19 |
| 1553 | Cloth face mask fit and function for children part one: design exploration Commercially available children’s cloth masks range widely in material type and fabric structures, methods of construction, layering, and shape, and there is a lack of sizing systems, anthropometric data or guidelines specifically targeting the fit assessment and design of cloth face masks for children 4-6 years old. To better identify and understand the cloth face mask fit and functional needs of children ages 4-6 years old, the researchers embarked on interdisciplinary in-depth study to investigate commercial market offerings of children’s face masks, identify consumer perspectives, and explore mask design improvements through design research. By triangulating results from survey feedback, commercial market content analysis, and wear trial observations, the researchers were able to identify important design criteria that can be used in the improvement of children’s cloth face mask design: size, comfort, dexterity, movement, and thermal comfort. These criteria were used to iteratively develop new mask prototypes involving a 3D printed head form, traditional sewing and hand patternmaking skills, and the creation of multiple mask versions to explore the design criteria listed above. The designs were interpreted through Bye’s (2010) Problem-Based Design Research (PBDR) framework, which identifies common design research practices in the field on a spectrum and situates PBDR as a process centered on a problem as impetus for design through which artifacts are developed. | N/A | 2022 | | CORD-19 |
| 1554 | Prediction of respiratory droplets evolution for safer academic facilities planning amid COVID-19 and future pandemics: A numerical approach Airborne dispersion of the novel SARS-CoV-2 through the droplets produced during expiratory activities is one of the main transmission mechanisms of this virus from one person to another. Understanding how these droplets spread when infected humans with COVID-19 or other airborne infectious diseases breathe, cough or sneeze is essential for improving prevention strategies in academic facilities. This work aims to assess the transport and fate of droplets in indoor environments using Computational Fluid Dynamics (CFD). This study employs unsteady Reynolds-Averaged Navier-Stokes (URANS) simulations with the Euler-Lagrange approach to visualize the location of thousands of droplets released in a respiratory event and their size evolution. Furthermore, we assess the dispersion of coughing, sneezing, and breathing saliva droplets from an infected source in a classroom with air conditioning and multiple occupants. The results indicate that the suggested social distancing protocol is not enough to avoid the transmission of COVID-19 since small saliva droplets ( ≤ 12 μm) can travel in the streamwise direction up to 4 m when an infected person coughs and more than 7 m when sneezes. These droplets can reach those distances even when there is no airflow from the wind or ventilation systems. The number of airborne droplets in locations close to the respiratory system of a healthy person increases when the relative humidity of the indoor environment is low. This work sets an accurate, rapid, and validated numerical framework reproducible for various indoor environments integrating qualitative and quantitative data analysis of the droplet size evolution of respiratory events for a safer design of physical distancing standards and air cleaning technologies. | N/A | 2022 | | CORD-19 |
| 1555 | COVID-19 Misinformation on Social Media and Public's Health Behavior: Understanding the Moderating Role of Situational Motivation and Credibility Evaluations The spread of misinformation on social networking conduit regarding COVID-19 pandemic poses deleterious consequences on public health. The author advance the body of knowledge on tackling misinformation to generate positive health behavior responses by proposing a conceptual framework based on the theory of persuasion and behavior change. Furthermore, as a belief antecedent, conspiracy theory is also used in this study. The author, using structural equation modeling technique, explored the three hundred seventy-three participants’ belief in conspiracy theory and religious misinformation and their influence on intention and behavior. Those direct relationships were tested by the joint moderating role of situational motivation and credibility evaluations. The study revealed that the situational motivation and credibility evaluation jointly and individually (in some cases) weaken the strong positive relationship between misinformation (conspiracy theory and religious misinformation) and health belief, health belief and intention, and intention and health behavior regarding COVID-19. The findings of this study offer guideline for policymakers to generate favorable health behavior regarding COVID-19 and any other epidemic or pandemic. Directions for researchers to any further extensions are also placed. | N/A | 2022 | | CORD-19 |
| 1556 | American Academy of Nursing Expert Panel Consensus Statement on the The Impact of COVID-19 on the US Economy, Education and Environment | Nurs Outlook | 2022 | | CORD-19 |
| 1557 | How gen Z can improve community literacy about the 17 SDGs? A realistic approach to construct a futuristic change-maker paradigm Many fields and different approaches have undergone a crucial merging of implications and have been co-involved in the developing and/or implementation of the 17-SDGs concepts. However, little has been done on the role of the generation Z who is transforming the workplaces and societies by creating and interpreting trends. The objectives of this research are to provide perspectives from the world about the generation Z participatory role and supporting contribution among their communities to reaching SDGs, and to illustrate their active role in a Futuristic Change-Maker Paradigm. A general review was conducted to explore the existing data on governance mechanisms for SDGs implementation regarding the multi-dimensional layers (social, economic, environmental, health, policies, communication, and technology) of the sustainable development structure that need to be considered in a systemic-sensitive approach. Various channels of youth participation can be associated with different levels of social and communities’ commitment. In this sense, this article; 1) confirms that generation Z could play an active role in utilizing state-of-the-art opportunities to address the established current UN-SDGs agenda, and 2) suggests how communication and science journalism can be conceptualized as a development intervention to go beyond the 2030 SDGs agenda. This study recommends several innovative areas for the integration of generation Z insights and activities as a basis for exploring the potential of this generation to improve communities’ literacy and behaviors about the 17-SDGs. This study ends with a practical and theoretical consideration to build a Futuristic Change-Maker Paradigm that can be extrapolated to other countries in their advance towards sustainability and SMART environmental management. | N/A | 2022 | | CORD-19 |
| 1558 | Covid-19 Vaccine safety and adverse event analysis from Pakistan Covid immunization commenced on 2nd Feb 2021 in Pakistan and as of 7th Sep 2021, there had been over 84 million vaccine doses received in Pakistan, of which 72% procured by the government, 22% received through Covax and 6% were donated. The vaccines rolled out nationally included: Sinopharm, Sinovac and CanSinoBIO (China), AstraZeneca (UK), Moderna and Pfizer (USA), Sputnik (Russia), and PakVac (China/Pakistan). About half of the eligible population in Pakistan (63m) have had received at least one dose of Covid vaccine as of Sep 2021. Pakistan National Pharmacovigilance Centre (PNPC) in coordination with WHO, MHRA and Uppsala Monitoring Centre (UMC) established pharmacovigilance centers across Pakistan. The Covid vaccine AEFIs in Pakistan were mainly reported via NIMS (National Immunization Management System), COVIM (COVID-19 Vaccine Inventory Management System), 1166 freephone helpline and MedSafety. There have been 39,291 ADRs reported as of 30th Sept 2021, where most reported after the first dose (n=27,108) and within 24-72h of immunization (n=27,591). Fever or shivering accounted for most AEFI (35%) followed by injection-site pain or redness (28%), headache (26%), nausea/vomiting (4%), and diarrhoea (3%). There were 24 serious AEFIs have been reported that were investigated in detail by the National AEFI review committee. The rate of AEFIs reports ranged from 0.27-0.79 per 1000 for various Covid vaccines in Pakistan that is significantly lower than the rates in UK for instance (∼4 per 1000). Finally, Covid vaccines were well tolerated and no significant cause for concern was flagged up in Pakistan's covid vaccine surveillance system concluding overall benefits outweighs risks. | N/A | 2022 | | CORD-19 |
| 1559 | Spatio-temporal changes pattern in the hotspot's footprint: a case study of confirmed, recovered and deceased cases of Covid-19 in India Hotspot detection and the analysis for the hotspot's footprint recently gained more attention due to the pandemic caused by the coronavirus. Different countries face the effect of the virus differently. In India, very little research has been done to find the virus transmission. The paper's main objective is to find changing pattern of the footprint of the hotspot. The confirmed, recovered, and deceased cases of the Covid-19 from April 2020 to Jan 2021 is chosen for the analysis. The study found a sudden change in the hotspot district and a similar change in the footprint from August. Change pattern of the hotspot's footprint will show that October is the most dangerous month for the first wave of the Corona. This type of study is helpful for the health department to understand the behavior of the virus during the pandemic. To find the presence of the clustering pattern in the dataset, we use Global Moran’s I. A value of Global Moran’s I greater than zero shows the clustering in the data set. Dataset is temporal, and for each type of case, the value Global Moran’s I > 0, shows the presence of clustering. Local Moran’s I find the location of cluster i.e., the hotspot. The dataset is granulated at the district level. A district with a high Local Moran’s I surrounded by a high Local Moran’s I value is considered the hotspot. Monte Carlo simulation with 999 simulations is taken to find the statistical significance. So, for the 99% significance level, the p-value is taken as 0.001. A hotspot that satisfies the p-value threshold is considered the statistically significant hotspot. The footprint of the hotspot is found from the coverage of the hotspot. Finally, a change vector is defined that finds the pattern of change in the time series of the hotspot’s footprint. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s41324-022-00443-8. | N/A | 2022 | | CORD-19 |
| 1560 | Post-covid China: 'vaccine diplomacy' and the new developments of Chinese foreign policy The COVID-19 pandemic that hit the world in early 2020 changed it unimaginably. China was forced to face many new challenges at the international level, not only those related to the handling of a health crisis. After overcoming the first wave of the pandemic, China had to focus on foreign policy and public diplomacy efforts to secure its main interests. As the world continues to struggle with COVID-19, China is using the pandemic for its own foreign policy purposes, mainly by using vaccines as a new foreign policy tool. The purpose of the research is to investigate the position of recent Chinese ‘vaccine diplomacy’ with reference to its traditional and contemporary public diplomacy and foreign policy strategies. The investigation has a qualitative character and is based on a content analysis of official press conferences conducted by the Chinese Ministry for Foreign Affairs. | N/A | 2022 | | CORD-19 |
| 1561 | Psychological Impact of the COVID-19 Pandemic on Families of People with Severe Mental Disorders Participating in Community Peer Support Groups in Brazil People with severe mental disorders are at increased risk of dying from COVID-19 and more susceptible to the impacts of the pandemic. This study aims to understand how the families of patients with severe mental disorders followed up in community peer support groups experienced the beginning of the pandemic in Brazil and how they fared during the period of restricted physical contact. Family members (n = 82) and patients (n = 27) belonging to community groups in Rio de Janeiro responded to an online survey that included assessments of quality of life and well-being along with open-ended questions. Thematic analysis of the answers showed that the majority of remarks were positive, despite the concerns, fears, and feelings common at the time. Positive feelings were also mentioned significantly. These findings demonstrate that this population was adaptive and resilient in coping with the restrictions on physical contact. The main concerns and difficulties of this population are discussed. | N/A | 2022 | | CORD-19 |
| 1562 | The Rivers of Dharma in the Face of Religious Challenges: A Comparative Analysis of Three Japanese Buddhist Temples in Brazil The article aims to develop a comparative reflection in view of three Japanese Buddhist temples: the Honpa Honganji (connected to the True Pure Land School); the Hompoji (Honmon Butsuryū Shū), and the Dokozan Busshinji (Sōtō Zen), located in the North of the State of Paraná, more specifically in the cities of Londrina and Rolândia (Brazil). As sources, materials derived from fieldwork are used, as well as interviews conducted with monks and practitioners. From the theoretical point of view, religion is understood as a symbolic system, as proposed by Clifford Geertz, open to the possibility of appropriations, according to Michel de Certeau. In addition, certain propositions of Michael Pye regarding religious transplantation are used. As a discussion, it is suggested that the circumscribed temples develop different responses to the problem of the death of first-generation immigrants and the discontinuity of the Japanese language in Brazil. The comparison is made through three parameters: the profile of the monks, the language used in materials and preaching, and the characteristics of the faithful. | N/A | 2022 | | CORD-19 |
| 1563 | COVID-19 and Kidney Involvement-A Systematic Review Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has resulted in an ongoing worldwide pandemic since it was first recognized in December 2019. The kidney is one of the organs most easily affected by COVID-19. The injury of the kidney by COVID-19 manifested as hematuria, proteinuria, serum creatinine fluctuations, and even acute kidney injury (AKI). Critically ill patients with COVID-19 are much more prone to suffer from AKI. Moreover, AKI is related to poor outcomes in the patients infected with SARS-CoV-2. Therefore, early detection and active prevention of kidney injury are very important. In this article, we reviewed the epidemiology, clinical characteristics, pathogenesis, pathological manifestations, treatment, and prognosis of kidney injury in patients with COVID-19. It is expected to provide valuable insights for disease prevention and control from the perspective of nephrologists. | N/A | 2021 | | CORD-19 |
| 1564 | COVID-19 Acute Kidney Injury: Current Knowledge and Barriers of Research | N/A | 2021 | | CORD-19 |
| 1565 | COVID-19 Associated Acute Kidney Injury Garners More Attention | N/A | 2021 | | CORD-19 |
| 1566 | Clinical Analysis of Kidney Injury in Elderly Patients with COVID-19 OBJECTIVE: The aim of the study was to analyze the clinical features of elderly patients with coronavirus disease 2019 (COVID-19) and to explore the relationship between COVID-19 patients and kidney injury. METHODS: A total of 188 elderly patients with confirmed COVID-19 enrolled in this study were hospitalized for at least 1 week in the Central Theater Command General Hospital of Chinese People's Liberation Army from January 3, 2020 to March 14, 2020. The recorded information included clinical data and results of kidney-related laboratory tests. Retrospective analysis was performed. RESULTS: The median age of the patients was 69 years (interquartile range 65–78, range: 60–97 years); 31.4% were 60–74 years old, and 68.6% were over 75 years old. A total of 12.8% and 18.6% of the patients were in critical and severe stages of COVID-19, respectively. The proportions of patients using mechanical ventilators and deaths were 9.5% and 8.5%, respectively. A total of 26.1% and 8.5% of the patients showed mild elevation of blood urea nitrogen (BUN) and serum creatinine (SCr) levels at admission. A total of 18.6% and 5.9% of the patients had elevated BUN and SCr 1 week after admission, respectively. A total of 3.1% of the patients were diagnosed with acute kidney injury, and 75% of those patients had chronic kidney disease before admission. Compared with the patients aged 60–74 years, those over 75 years exhibited significantly increased proportions of elevated BUN levels, critical illness, use of mechanical ventilated, and death. Multivariate logistic regression analysis revealed that an elevated BUN level at admission and 1 week after admission were independent risk factors for death in the elderly patients with COVID-19. CONCLUSION: There were more critical cases and a high mortality in elderly patients with COVID-19. An increased BUN level was an independent risk factor for death in elderly patients with COVID-19. | N/A | 2021 | | CORD-19 |
| 1567 | Patients with Chronic Kidney Disease Have Higher Acute Kidney Injury Morbidity than those without after SARS-CoV-2 Infection BACKGROUND AND OBJECTIVES: Chronic kidney disease (CKD) and acute kidney injury (AKI) increase the risk of serious disease and mortality in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-infected patients. This study evaluated the occurrence and outcome of AKI in CKD and non-CKD patients infected with SARS-CoV-2. SUBJECTS AND METHODS: We retrospectively analyzed the medical records of 845 patients with SARS-CoV-2 infection regarding the occurrence and outcome of AKI in a coronavirus disease-2019 (COVID-19)-designated hospital in Wuhan, China, from December 31, 2019, to March 20, 2020. RESULTS: Of the 845 COVID-19 patients, 91 had CKD and 754 had no CKD (non-CKD), of whom 22 and 14 developed AKI, respectively. Finally, 36 patients were included in the analysis. Older patients and those with cardiovascular or cerebrovascular diseases were more likely to develop AKI. More CKD patients progressed to critical illness (72.73%) than non-CKD patients (57.14%), but the degree of AKI in CKD patients was lesser than that in non-CKD patients. Higher urea nitrogen, creatinine, and proteinuria levels were observed in CKD patients. More non-CKD patients were treated with human albumin than CKD patients. The survival probability of CKD patients was lower than that of non-CKD patients, but it was not statistically significant. CONCLUSION: There were significant differences in the incidence rate of AKI after SARS-CoV-2 infection between CKD and non-CKD patients, and the clinical manifestations and treatments of AKI also differed. These results highlight the necessity of variable treatment methods for optimal clinical management. | N/A | 2021 | | CORD-19 |
| 1568 | OCCUCON 2022 Abstracts | Indian J Occup Environ Med | 2022 | | CORD-19 |
| 1569 | Thirty years of China-Russia strategic relations: achievements, characteristics and prospects With 3 decades of steady development, China–Russia relations have entered their best period in history and increasingly become a model of major-country diplomacy with Chinese characteristics in the new era. They were smoothly transformed after the disintegration of the Soviet Union and went through in-depth development from being a constructive partnership to a strategic partnership of coordination and then a comprehensive strategic partnership of coordination for the new era. In terms of the strategic, multi-dimensional, and pragmatic nature of bilateral cooperation, the relations have become more fruitful since 2012, with increased collaboration in such areas as international mechanisms, military technologies and energy. While there have always been factors that could have a negative impact on bilateral relations, they have been defused or managed well on the basis of high-level political mutual trust and through good communication between leaders of the two countries. The author believes that no matter what changes take place in the international situation and regional environment, the purpose of good-neighborly and friendly cooperation and the principle of mutual support, mutual benefit, and win–win will not change. | N/A | 2022 | | CORD-19 |
| 1570 | Application of NLP-based topic modeling to analyse unstructured text data in annual reports of construction contracting companies The construction industry is the backbone of a nation’s economy. It is a matter of great concern that such an industry suffers from time and cost overruns, especially in these challenging times. Coupled with the overrun issues, the sector is often criticized for lacking adequate quality and quantity of structured secondary data. The emerging technologies in data science and machine intelligence present a unique opportunity to understand the sector better and aid in effective decision-making. To better understand the utility of such technologies, the Management Discussion and Analysis ssections of the annual reports of publicly listed top Indian construction contracting firms are analyzed to identify the presence of ‘strategy themes’ and further map them to the organizations considered. Natural Language Processing (NLP)-based topic modeling algorithms, namely Latent Dirichlet Allocation (LDA) and Non-negative Matrix Factorization (NMF), are used in this study to perform a qualitative content analysis to identify the latent themes. From a methodological standpoint, considering the context of this study, the NMF results are better in accuracy, precision, and recall compared with the LDA. The results show that while most construction contracting firms prioritized a ‘revenue-focused’ strategy to expand their order books, a smaller set of large-sized firms seem to prioritize process improvement to improve their execution productivity and therefore are ‘profit margin improvement focused’ or ‘lean-focussed’ in their approach. Although a proof-of-concept, this study unlocks the immense potential of unsupervised NLP-based topic-modeling tools to understand and infer from unstructured and freely available text data in the public domain to aid sectoral analysis and policymaking. | N/A | 2022 | | CORD-19 |
| 1571 | Multimodality radionuclide imaging in fever of unknown origin presenting with a solitary spleen lesion BACKGROUND: Fever of unknown origin (FUO) still represents a serious challenge for clinicians, since it can be related to a wide spectrum of disorders, ranging from infections to malignancies. In this scenario, nuclear medicine can be of value to achieve a correct diagnosis both through positron emission computed tomography (PET/CT) and (99m)Tc labeled hexamethylpropylene amine oxime (HMPAO) white blood cell (WBC) scintigraphy. CASE PRESENTATION: We are presenting the case of 65-year-old male, who was referred to our hospital due to prolonged unexplained fever. He was submitted to abdomen ultrasonography (US) that did not disclose relevant pathological findings. Subsequently, he underwent PET/CT scan with (18)F-fluorodeoxyglucose ((18)F-FDG) that revealed an area of increased tracer uptake in splenic inferior pole. In order to solve differential diagnosis between tumor and infection, he was submitted to (99m)Tc-HMPAO WBC scintigraphy that resulted negative for sites of pathologic radiolabeled cells’ accumulation but revealed a photopenic area in the splenic inferior pole. The pattern of mismatched uptake between (18)F-FDG PET/CT and (99m)Tc-HMPAO WBC scintigraphy was considered highly suspicious for spleen tumor localization. The patient was scheduled for splenectomy and histology resulted positive for non-Hodgkin lymphoma (NHL) of diffuse large B cell type. After splenectomy, a further (18)F-FDG PET/CT revealed the appearance of hypermetabolic hepatic lesions. The patient underwent chemotherapy with complete remission. CONCLUSION: Nuclear medicine provides valuable tools for differential diagnosis in FUO. In case of patients presenting solitary lesion of the spleen, the combined use of (18)F-FDG PET/CT and (99m)Tc-HMPAO WBC scintigraphy can provide relevant information to aid clinicians to a correct diagnosis. | N/A | 2022 | | CORD-19 |
| 1572 | Contrast-enhanced spectral mammographic findings of phyllodes tumor of the breast BACKGROUND: Phyllodes tumors of breast are rare fibroepithelial neoplasms. They have similar radiological findings with fibroadenomas. While fibroadenomas are benign lesions, phyllodes tumors may have malignant potential. Therefore, any imaging findings to differentiate fibroadenoma from phyllodes tumor are valuable. CASE PRESENTATION: A 51-year-old female patient was admitted to our clinic with the complaint of a palpable mass. Tru-Cut biopsy resulted as phyllodes tumor, and excision was recommended. However, the patient neglected herself during the COVID-19 pandemic, and 20 months later, she presented with a huge and complex mass. On CESM imaging, cystic areas and clefts were identified. The case was diagnosed as borderline phyllodes tumor. CONCLUSIONS: Although MRI findings of phyllodes tumor are well known and reported many times, there is no information about CESM findings of this tumor in literature. Bubbly appearance on CESM is useful finding in the diagnosis of phyllodes tumor of breast. | N/A | 2022 | | CORD-19 |
| 1573 | The dental office: A safe place against COVID-19 and other future pandemics Background The pandemic caused by the spread of COVID19 generated throughout the world great changes in all areas of life. Social distancing was carried out very drastically in some countries, and even in the field of dental care, some countries prohibited the practice of dentistry. Objective To demonstrate that the dental office is safe regarding the possibility of contagion of SRasCov2 as long as good biosecurity protocols are used. Methods A structured survey of 19 questions was applied to 103 patients who subsequently attended a periodontics and oral and maxillofacial surgery office in Mexico to receive care from these specialties between April 2020 and July 2021. The questions posed in this survey were aimed at knowing the opinion of the patients regarding the measures that this establishment has for the prevention of the transmission of COVID19, as well as questions regarding the possible effects of attending this office in contagion of the disease from patients and their families. Results A total of 18 (17.5%) patients reported having suffered COVID19, and none reported that they fell ill after the consultation. None of the clinic's specialists and assistants have fallen ill with COVID-19 during the pandemic. Conclusions It is not necessary to suspend or condition dental care during times of pandemics such as what happened with COVID19, as long as strict safety protocols are observed within clinical facilities. | N/A | 2022 | | CORD-19 |
| 1574 | Retrospective analysis of biochemical markers in COVID-19 intensive care unit patients BACKGROUND: The aim of the study was to evaluate the presence and effects of hematological and biological parameters in the diagnosis of the disease by performing blood tests on COVID-19 patients admitted to the intensive care unit (ICU). RESULTS: Biochemical parameters from the blood samples of 279 patients who were confirmed to have COVID-19 and met the criteria for admission to the ICU were compared between discharged and deceased patients. Multiple logistic regression analysis was performed in terms of mortality and probability of being discharged. The predictive value of serum C-reactive protein (CRP), procalcitonin (PCT), lymphocyte, neutrophil, leucocyte, and platelet (PLT) levels was evaluated by measuring the area under the receiver operating characteristic curve (AUROC). Comparisons made according to deceased and survival patients results revealed that while no statistically significant difference was observed between test groups lymphocyte and platelet-lymphocyte ratio values, statistically significant difference was found between the test groups regarding platelet, leukocyte, neutrophil, PCT, neutrophil-lymphocyte ratio (NLR), and thrombocyte count × neutrophil count/lymphocyte count (SII) values. CONCLUSIONS: This study showed that biochemical parameters examined are important in determining the prognosis of the disease and may be useful in determining the direction of the treatment process and predicting the risk of discharge or death after the initial evaluation of the patients in the ICU. | N/A | 2022 | | CORD-19 |
| 1575 | Borders and identities in NI after Brexit: remaking Irish-UK relations The process of de-Europeanisation initiated by the British Government’s form of Brexit poses a major threat to the maintenance of peace in Northern Ireland (NI). This paper contends that a hard Brexit and active dismantling of ties to the European Union (EU) pursued by the Johnson Administration is fundamentally incompatible with the provisions of the 1998 Good Friday Agreement (GFA). It is acknowledged that the EU institutions were not directly responsible for achieving the relative peace that resulted. Yet, the EU provided a constructive context for societal normalisation. Shared EU membership improved engagement between the British and Irish governments, fostering ‘habits of co-operation’. It afforded a shared political space that helped transcend binary political, religious and ethnic differences. The implications of Brexit that entails active de-Europeanisation and resulting tensions concerning the NI protocol are therefore significant. Yet, this paper maintains that the long-term impact of Brexit remains uncertain. For instance, it is not clear that a ‘hard’ Brexit will inevitably result in the unification of Ireland. Deadlock marked by prolonged instability appears likely, provoking the re-emergence of sectarian violence. The paper addresses such themes by placing borders and identities at the centre of its analytical framework. | N/A | 2022 | | CORD-19 |
| 1576 | Reimaging eLearning technologies to support students: On reducing transactional distance at an open and distance eLearning institution Transactional distance continues to be a major issue in Distance Education (DE) as resolutions to guarantee and support it are not wholly contingent on technological affordances, but depend on interactions, communication, and motivational channels embedded in pedagogical practices. While education during the Covid-19 pandemic is supported by DE, discussions around academic achievement during the pandemic have also begun. This paper argues that without reducing the transactional distance between the lecturers and students in DE institutions, effective teaching and learning cannot occur. This is a qualitative, participatory action research study that uses the experiences of first-year students, interviews from lecturers and observations of the online activity of the students in one academic writing module. This paper draws on one DE University as an example, the University of South Africa. The purpose of the paper is to identify and suggest alternative pedagogical practices to reduce the transactional distance between students and lecturers. | N/A | 2022 | | CORD-19 |
| 1577 | Myokine Response to Blood-Flow Restricted Resistance Exercise in Younger and Older Males in an Untrained and Resistance-Trained State: A Pilot Study PURPOSE: The purpose of this study was to examine the response of myokines to blood-flow restricted resistance-exercise (BFR-RE) in younger and older males before and after completing a 12-week resistance-training program. METHODS: There were 8 younger (24.8 ± 3.9 yrs) and 7 older (68.3 ± 5.0 yrs) untrained male participants completed this study. Anthropometric and maximal strength (1RM) measurements were collected before and after a 12-week, supervised, progressive full-body resistance-training program. As well, an acute bout of full-body BFR-RE was performed with venipuncture blood samples collected before and immediately following the BFR-RE, followed by sampling at 3, 6, 24 and 48 h. RESULTS: The 12-week training program stimulated a 32.2% increase in average strength and 30% increase in strength per kg of fat free mass. The response of particular myokines to the acute bout of BFR-RE was influenced training status (IL-4, untrained = 78.1 ± 133.2 pg/mL vs. trained = 59.8 ± 121.6 pg/mL, P = 0.019; IL-7, untrained = 3.46 ± 1.8 pg/mL vs. trained = 2.66 ± 1.3 pg/mL, P = 0.047) or both training and age (irisin, P = 0.04; leukemia inhibitory factor, P < 0.001). As well, changes in strength per kg of fat free mass were correlated with area under the curve for IL-4 (r = 0.537; P = 0.039), IL-6 (r = 0. 525; P = 0.044) and LIF (r = − 0.548; P = 0.035) in the untrained condition. CONCLUSION: This study identified that both age and training status influence the myokine response to an acute bout of BFR-RE with the release of IL-4, IL-6 and LIF in the untrained state being associated with changes in strength per kg of fat free mass. | N/A | 2022 | | CORD-19 |
| 1578 | Amphotericin-B-liposomal/antibacterials/immunosuppressants: Various infections, nephrotoxicity and off-label use: 4 case reports | N/A | 2022 | | CORD-19 |
| 1579 | Dexamethasone: Bordetella hinzii pneumonia and pulmonary aspergillosis: case report | N/A | 2022 | | CORD-19 |
| 1580 | Tozinameran: Immunogloblin A nephropathy, fever and headache: case report | N/A | 2022 | | CORD-19 |
| 1581 | Elementary teachers' experience of engaging with Teaching Through Problem Solving using Lesson Study For many decades, problem solving has been a focus of elementary mathematics education reforms. Despite this, in many education systems, the prevalent approach to mathematics problem solving treats it as an isolated activity instead of an integral part of teaching and learning. In this study, two mathematics teacher educators introduced 19 Irish elementary teachers to an alternative problem solving approach, namely Teaching Through Problem Solving (TTP), using Lesson Study (LS) as the professional development model. The findings suggest that the opportunity to experience TTP first-hand within their schools supported teachers in appreciating the affordances of various TTP practices. In particular, teachers reported changes in their beliefs regarding problem solving practice alongside developing problem posing knowledge. Of particular note was teachers’ contention that engaging with TTP practices through LS facilitated them to appreciate their students’ problem solving potential to the fullest extent. However, the planning implications of the TTP approach presented as a persistent barrier. | N/A | 2022 | | CORD-19 |
| 1582 | Multiple drugs: Central serous chorioretinopathy and off label use: case report | N/A | 2022 | | CORD-19 |
| 1583 | Antineoplastics/granulocyte colony-stimulating factors: Febrile neutropenia, COVID-19 and aggravation of COVID-19 pneumonia and post-COVID-19 organising pneumonia: case report | N/A | 2022 | | CORD-19 |
| 1584 | AZD-1222: Aseptic meningitis: case report | N/A | 2022 | | CORD-19 |
| 1585 | Multiple drugs: Various toxicities: 3 case reports | N/A | 2022 | | CORD-19 |
| 1586 | Other adverse reaction research | N/A | 2022 | | CORD-19 |
| 1587 | FDA limits authorised use of Janssen COVID-19 vaccine | N/A | 2022 | | CORD-19 |
| 1588 | Fentanyl/midazolam/propofol abuse: Loss of consciousness: case report | N/A | 2022 | | CORD-19 |
| 1589 | Epinephrine: Lack of efficacy: case report | N/A | 2022 | | CORD-19 |
| 1590 | Corticosteroids/methotrexate/sars-cov-2-vaccine-inactivated-sinovac-biotech/tozinameran: Bullous pemphigoid, exacerbation of bullous pemphigoid and SARS-COV-2 infection: 7 case reports | N/A | 2022 | | CORD-19 |
| 1591 | Covid-19-vaccine-pfizer-biontech: Myasthenia gravis: case report | N/A | 2022 | | CORD-19 |
| 1592 | COVID-19-vaccine/plasma: Chronic inflammatory demyelinating polyneuropathy and lack of efficacy: case report | N/A | 2022 | | CORD-19 |
| 1593 | AZD-1222: Acute disseminated encephalomyelitis anti-MOG antibody-positive: case report | N/A | 2022 | | CORD-19 |
| 1594 | SARS-COV-2-vaccine-inactivated-Sinovac-Biotech: Severe proteinase 3 antineutrophil cytoplasmic antibody glomerulonephritis: case report | N/A | 2022 | | CORD-19 |
| 1595 | Iodine-131: Lack of efficacy: case report | N/A | 2022 | | CORD-19 |
| 1596 | Azithromycin/favipiravir/hydroxychloroquine: Various toxicities: 7 case reports | N/A | 2022 | | CORD-19 |
| 1597 | Elevated Vulnerability of Chronic Leukemia Patients to COVID-19 Infection: A Systems Biology Approach BACKGROUND: Emerging evidence has shown that SARS-CoV-2 may affect the circulatory system in addition to the human respiratory system. However, no study has indicated whether patients with leukemia have a greater likelihood of SARS-CoV-2 infection or have poor treatment outcomes. OBJECTIVE: The study aimed to demonstrate the relationship between essential blood proteins and the major SARS-CoV-2 proteins by network pharmacology bioinformatics analysis. METHODS: Bioinformatics analysis was used to establish eight differentially expressed gene hubs in leukemia through differential gene screening, protein–protein interaction network analysis, and gene enrichment analysis. Molecular docking analysis was also conducted to dock the two up-regulated proteins with the spike glycoprotein in leukemia and the critical protease enzyme (Mpro) of SARS-CoV-2. RESULTS: We identified two up-regulated genes (PTPRC and BCL6) among the eight differentially expressed genes. The PTPRC and BCL6 also docked perfectly with the main SARS-CoV-2 structural proteins. CONCLUSION AND RECOMMENDATION: This study indicates that SARS-CoV-2 is likely to affect with the blood in patients with chronic leukemia. Therefore, patients with chronic leukemia require greater medical attention and precautions during the COVID-19 pandemic. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s44229-022-00005-y. | N/A | 2022 | | CORD-19 |
| 1598 | Ad26.COV2-S: Cerebral venous thrombosis: case report | N/A | 2022 | | CORD-19 |
| 1599 | Allopurinol: Stevens Johnson syndrome/toxic epidermal necrolysis: case report | N/A | 2022 | | CORD-19 |
| 1600 | Multiple drugs: Pancytopenia, unmasking of myelodysplastic-syndrome and lack of efficacy: case report | N/A | 2022 | | CORD-19 |
