| Title | Venue | Year | Impact | Source |
| 6501 | Where horizontal and vertical surveillances meet: Sense-making of US COVID-19 contact-tracing apps during a health crisis Analyzing user reviews of seven US digital contact-tracing apps for COVID-19, this article unpacks how the new form of surveillance technology is understood and experienced by individuals during a global health crisis. The findings suggest that the app users felt empowered via self-tracking capacity and expressed community-level care and concerns, including those regarding the marginalized. At the same time, the users were raising doubts over technical effectiveness, navigating varying levels of voluntary choice available, and negotiating privacy concerns depending on the (dis)trust they held of institutional entities behind the governance of the apps. We argue that it is critical to investigate how surveillance technologies are situated across horizontal and vertical relationships in people's everyday lives to fully understand the individual and societal acceptance and/or refusal of the very systems during crises. | Mob Media Commun | 2022 | | CORD-19 |
| 6502 | Mitigation of SARS-CoV-2-Mediated Endothelial Injury via Suppression of the Epigenetic Enzyme KMT2A/MLL1 in Macrophages | J Vasc Surg Venous Lymphat Dis | 2022 | | CORD-19 |
| 6503 | Microengineered Human Vein-Chip Recreates Venous Valve Architecture and its Contribution to COVID-19 induced Thrombosis | J Vasc Surg Venous Lymphat Dis | 2022 | | CORD-19 |
| 6504 | Prediction of Symptomatic Venous Thromboembolism in Covid-19 Patients: A Retrospective Comparison of Caprini, Padua and IMPROVE-DD Scores | J Vasc Surg Venous Lymphat Dis | 2022 | | CORD-19 |
| 6505 | Anticoagulation in COVID-19-positive Patients on Venovenous ECMO | J Vasc Surg Venous Lymphat Dis | 2022 | | CORD-19 |
| 6506 | Sensitivity analysis of COVID-19 with quarantine and vaccination: A fractal-fractional model To eradicate most infectious diseases, mathematical modelling of contagious diseases has revealed that a combination of quarantine, vaccination, and cure is frequently required. However, eradicating the disease will remain a difficult task if they aren't provided at the appropriate time and in the right quantity. Control analysis has been shown to be an effective way for discovering the best approaches to preventing the spread of contagious diseases through the development of disease preventive interventions. The method comprises reducing the cost of infection, implementing control measures, or both. In order to gain a better understanding of COVID-19's future dynamics, this study presents a compartmental mathematical model. The problem is modelled as a highly nonlinear coupled system of classical order ODEs, which is then generalised using the Mittag-Leffler kernel's fractal-fractional derivative. The uniqueness of the fractional model under discussion has also been demonstrated. The boundedness and non-negativity of the considered model are also established. The next generation technique is used to examine basic reproduction, anddisease free and endemic equilibrium. We used reported cases from Australia in this investigation due to the high risk of infection. The reported cases are considered between 1st July 2021 and 20th August 2021. On the basis of previous data, the spread of infection is predicted for the next 600 days which is shown through different graphs. The graphical solution of the considered nonlinear model is obtained via numerical scheme by implementing the MATLAB software. Based on the fitted values of parameters, the basic reproduction number R 0 is calculated as R 0 ≈ 1.58276 . Furthermore, the impact of fractional and fractal parameter on the disease spread among different classes is demonstrated. In addition, the impact of quarantine and vaccination on infected people is dramatically depicted. It's been argued that public awareness of the quarantine and effective vaccination can drastically reduce infection rates in the population. | N/A | 2022 | | CORD-19 |
| 6507 | HP37: Critical illness polyneuropathy in COVID-19 patients: A case-control study Introduction: The coronavirus SARS CoV-2 (COVID-19) could cause damage to neural tissue. This injury is responsible for neuromuscular disturbance after the onset of respiratory symptoms in these patients. Objective: is to analyze the characteristics of all patients diagnosed with critical illness polyneuropathy (CIP) reported from March 2020 to March 2021 in the Clinical Neurophysiology Department from La Princesa University Hospital. Methods: Patients were classified into two groups 17 patients admitted to the hospital with confirmed COVID-19 (Cases Group, CaG) and 12 patients without COVID-19 infection (Control Group, CoG). We performed both electroneurography and electromyography. Results: The distribution of the subtypes of the CIP was as follows: axonal motor polyneuropathy (24% in CaG vs 25% in CoG), axonal sensorimotor polyneuropathy (35% in CaG vs 58% in CoG), and mixed sensorimotor polyneuropathy (41% in CaG vs 16% in CoG). Needle EMG showed spontaneous activity in 100% in CaG vs 75% in CoG. The days of hospitalisation were 64.8 ± 7.9 in the CaG and 54.5 ± 9.9 in the CoG. Favourable evolution was observed in the 35% in CaG vs 42% in CoG, and unfavourable evolution was observed in the 41% in CaG vs 33% in CoG. Conclusion: We highlighted the nerves damaged in patients infected by COVID-19 and admitted to the Intensive Care Unit. Viral neuropathy is thought to be primarily axonal; however, we observe a high prevalence of demyelinating injuries in patients affected with this infection. Considering these results, we focus on the importance of early neurorehabilitation to improve nerve function. | Clin Neurophysiol | 2022 | | CORD-19 |
| 6508 | HP36: Diaphragm impairment in patients with COVID-19: A case-control study Objective: Physicians have observed ventilation disorders in patients with COVID-19. The possible impairment of the diaphragm could be related to the systemic inflammatory response that typifies this infection. We aimed to assess the diaphragmatic function in patients with severe COVID-19. Methods: We recruited patients admitted with pneumonia and positive PCR for SARS-CoV-2, differentiating two groups according to their respiratory symptoms. The cases group consisted of 9 inpatients with moderate-severe dyspnea, pain with diaphragmatic origin or hiccup. The control group consisted of 10 inpatients who suffered from mild dyspnea. We performed phrenic nerve electroneurogram and diaphragmatic ultrasound to assess the diaphragmatic function. Results: We observed differences in the amplitude of evoked potentials, being 25.92% (SEM:7.22) in the cases group vs 19.81% (SEM:5.27) in the control group (p = 0.711). The right diaphragm thickness mean was 46.67% (SEM:8.86) in the cases group vs 62.15% (SEM:5.58) in the control group (p = 0.432), the left diaphragm thickness mean was 57.89% (SEM:15.36) in the cases group vs 73.34% (SEM:6.74) in the control group (p = 0.730), the right expiratory fraction mean was 0.53 (SEM:0.11) in the cases group vs 0.59 (SEM:0.05) in the control group (p = 0.674), and the left expiratory fraction mean was 0.58 (SEM:0.15) in the cases group vs 0.73 (SEM:0.07) in the control group (p = 0.195). Conclusion: Although diaphragmatic dysfunction is difficult to detect, our combined functional and morphological approach with electroneurograms and ultrasounds could improve diagnostic sensitivity. We suggest that diaphragmatic dysfunction could play a relevant role in respiratory failure in patients with COVID-19. | Clin Neurophysiol | 2022 | | CORD-19 |
| 6509 | HP47: Post covid optic neuritis,Egyptian two case reports The exact incidence of neurological complications from coronavirus disease 2019 (COVID-19) infection remains unknown. Neurological symptoms are more common with severe form of the disease. Through neuro-invasion, the virus can affect both neurons and glial cells and induce wide range of neurological pathologies. CNS symptoms is commoner representing 91% of all neurological patients with 9% only with PNS. PNS manifestations showed variable results where visual impairment and nerve pains were more frequent in the severe COVID-19 category of patients. This is a 2 case report study of post covid optic neuritis , both after severe covid infection and hospitalization ,they developed acute onset visual affection mostly1.5 month in the first case and 2 month in the second one after almost complete cure. The first case had monocular delayed perception of vision , the second one had complete visual loss of one eye of unexplained causes. All neurological and ophthalmological investigations were normal apart from visual evoked potentials that showed small amplitude p100 response in the first case and absent response in the last one. This supports a study Based on murine models of other CoVs, stated that viral-induced optic neuritis secondary to autoantibody production against neuroretina should also be included in the differential diagnosis and infected patients should be monitored for signs of neuroretinal degeneration in the long term. | Clin Neurophysiol | 2022 | | CORD-19 |
| 6510 | HP38: Neurophysiological assessment of peripheral neuropathies associated with COVID-19 Neurological complications associated with COVID-19 are a significant cause of morbidity, affecting both central and peripheral nervous systems. We aim to assess the electrophysiological features of peripheral nerve injuries (PNI) in patients with COVID-19. Methods: We included 31 patients between March 2020 and April 2021 with a suspected diagnosis of PNI with COVID-19. We performed motor and sensory nerve conduction studies and electromyography (EMG) in the upper and lower extremities. Results: The mean age was 66.8±3.1 years (21 males, 10 females). A 96.7% (30 patients) were admitted to ICU, with a mean stay of 32.9±5.1 days. The neurophysiological examination showed, in descending order: mixed polyneuropathies 22.6% (7 patients), motor axonal polyneuropathies 19.4% (6 patients), sensorimotor axonal polyneuropathies 19.4% (6 patients), peroneal mononeuropathies 12.9% (4 patients), brachial plexopathies 12.9% (4 patients), Guillain-Barré syndrome (GBS) 6.4% (2 patients), Miller Fisher syndrome (MFS) 3.2% (1 patient) and femoral mononeuropathy 3.2% (1 patient). The low amplitude in both motor and sensory conduction studies was the most common neurophysiological finding except in GBS and MFS that showed prolonged distal latency and slow conduction velocity. EMG showed spontaneous activity in all patients. Conclusion: Our study shows the main neuropathy damage related to COVID-19 was critical illness polyneuropathy; however, we must consider mononeuropathies in these patients. There is broad evidence concerning the peripheral nervous system injury as a complication in patients hospitalized by COVID-19, being the neurophysiological tests a valuable tool to assess the peripheral nerve function. | Clin Neurophysiol | 2022 | | CORD-19 |
| 6511 | HP05: Diagnostic and prognostic assessment in respiratory and hemodynamic changes related to prone position in COVID-19 patients Objective: One of the most relevant findings of COVID-19 is the respiratory damage that leads to an impairment in tissue oxygenation during the course of the disease. To study this disease's physiopathology, we have analyzed the respiratory patterns and the hemodynamic variations related to postural changes in inpatients with COVID-19. Methods: We performed a prospective study including 11 polygraph and hemodynamic studies from inpatients admitted for COVID-19 who benefited from positional changes. To assess the respiratory parameters, we conducted polygraph studies. To evaluate the hemodynamic variables, we used a thoracic electrical bioimpedance. Results: We observed a minimum oxygen saturation median of 85.00% (IQR: 7.00) in the supine position vs 91.00% (IQR: 8.00) in the prone position (p=0.173). The airflow restriction in the supine position was 2.70% (IQR: 6.55) vs 1.55% (IQR: 2.80) in the prone position (p=0.383). We observed a slight tendency to decrease in all parameters in the prone position concerning the hemodynamic variables, although they were no statistically significant. We show a decrease in vascular resistance mean in the prone position, being 18.2% vs 36.4% in the supine position (p=0.871). Conclusion: Our report shows an improvement in oxygen saturation and airflow restriction related to the placement of the patient in the prone position. Also, we observed a mild enhancement in hemodynamic variables. The data shown is relevant because early identification of the more severe cases could help anticipate the clinical progression using the therapeutic oxygen measures necessary to avoid the disease's fatal progression. | Clin Neurophysiol | 2022 | | CORD-19 |
| 6512 | Breakthrough medicines during the COVID-19 pandemic era | Future Drug Discov | 2022 | | CORD-19 |
| 6513 | Survival Radiology: How a popular in-person interactive medical student radiology workshop pivoted online during the COVID-19 pandemic BACKGROUND: Survival Radiology (SR) is a flagship annual full-day in-person radiology workshop targeted at final year medical students in Singapore to prepare them for internship. Previous in-person editions have consistently received positive reviews from 2014 to 2019. However, the COVID-19 pandemic necessitated a rapid online pivot for its sixth edition in 2020. OBJECTIVES: This study aims to (a) identify key success factors of a traditional in-person medical student radiology workshop, (b) describe the rapid online pivot in 2020 and (c) to identify key success factors for online educational initiatives. METHODS: Post-workshop survey responses of SR from 2014 to 2020 were evaluated. Likert-scale data were quantitatively analysed, while free-text responses were qualitatively analysed. RESULTS: A total of 1248 post-workshop surveys (2014–2020 workshops) and 266 free-text responses (2020 workshop) were received from 2640 participants over the years. Progressive changes that sustained or improved participant feedback for in-person SR workshops included adoption of a case-based approach, utility of ‘live’ audience response systems and incorporation of quizzes with a favourable overall feedback rating of 4.42–4.89 from 2014 to 2019. The webinar version of SR in 2020 became the best-rated edition since inception with a rating of 4.9. Qualitative analysis of feedback from SR 2020 showed that the participants preferred the webinar model, online modes of engagement and interactivity. CONCLUSION: Our experience shows that it is not only possible to successfully pivot online for such workshops, but that blended educational formats utilising online engagements supplemented by in-person activities will be well-received by ‘Generation Z’ learners even after the COVID-19 pandemic. | N/A | 2022 | | CORD-19 |
| 6514 | Are we Truly "Safer-At-Home"? A Test of Contextual Effects on Mental Health and Drug Overdose Incidents During the COVID-19 Pandemic This study examined whether the social restrictions stemming from COVID-19 impacted the locations of mental health and drug overdose incidents, while controlling for immediate and community contextual indices. Addresses for mental health/overdose calls to law enforcement or emergency medical services between January 1, 2018 and August 13, 2020 were collected from one police department in the Midwestern United States. Businesses and previous victimization/offending were joined with parcels (level-1; N = 20,019), whereas local services and socioeconomic indicators were joined with block groups (level-2; N = 32), to allow for a multi-level (HLM7) examination of context on mental health/overdose incidents. Event Rate Ratios (ERR) revealed the greatest contextual effects took place following social distancing mandates. Findings highlight the importance of allocating to areas with the highest likelihood of reporting incidents and suggest that parcels with a history of sex offenses, drug offenses, and prior mental health calls may benefit the greatest from preventative resources. | J Drug Issues | 2022 | | CORD-19 |
| 6515 | THE NEOREALISM AND NEOLIBERALISM BEHIND INTERNATIONAL RELATIONS DURING COVID-19 The literature contains much discussion on the contemporary differences between neorealism and neoliberalism, especially in the context of international relations. However there have, as yet, been limited attempts to investigate how these international relations theories fare in explaining state responses to the COVID-19 outbreak. This study reviews the conceptual frameworks underpinning neorealism and neoliberalism and applies them to key state behaviors during the COVID-19 outbreak. Some examples of neorealism attached to the current pandemic include: criticism of the role of the World Health Organization, the closure of international borders, international competition to collect pharmaceutical products, bans on exports, richer states protecting their national interests, the international misuse of power during emergency orders, restrictions placed on the international media, and the deployment of military forces. By contrast, neoliberalism's focus on international cooperation is noted in U.S., Chinese, and other countries’ attempts to distribute knowledge and aid internationally, as well as in the efforts of key international organizations like the World Health Organization and the global Covax initiative. I offer an evidence-based conceptual framework using neorealism and neoliberalism to show how both have informed international behavior during the COVID-19 outbreak—although continued emphasis on the former shows few signs of abating as the pandemic approaches its third year. | N/A | 2022 | | CORD-19 |
| 6516 | Socio-Cultural Values Are Risk Factors for COVID-19-Related Mortality To assess whether socio-cultural values are population-level risk factors for health, I sought to predict COVID-19-related mortality between 2 weeks and 6 months after the first COVID-19-related death in a country based on values extracted from the World Values Survey for different country sets, after controlling for various confounding variables. COVID-19-related mortality was increased in countries endorsing political participation but decreased in countries with greater trust in institutions and materialistic orientations. The values were specific to COVID-19-related mortality, did not predict general health outcomes, and values predicting increased COVID-19-related mortality predicted decreased mortality from other outcomes (e.g., environmental-related mortality). | Cross Cult Res | 2022 | | CORD-19 |
| 6517 | The Online Strength-Informed Acceptance and Commitment Therapy Among COVID-19-Affected Adolescents Purpose: This study develops and investigates the changes in anxiety symptoms and quality of life (QoL) among participants of the online Strength-informed Acceptance and Commitment Therapy (SACT) across three tests. Methods: A small-scale, quasi-experiment with no control group was conducted. Repeated-measures analysis was employed to assess the changes of the three tests, which were the pre-experimental, post-test, and 3-month follow-up test. A total of 47 adolescents (ages 10–12) completed the 45-min intervention that lasted 10 weeks. Results: Compared with the pre-experimental, the post-test indicated significant anxiety symptoms reduction but not a statistically significant increase in QoL. The 3-month follow-up test indicated reduced anxiety symptoms and improved QoL compared with the pre-experimental. The with-in subject changes were substantial. Conclusions: The online SACT is a promising model to reduce anxiety symptoms and promote QoL among adolescents during the current COVID-19 pandemic, which show both short- and long-term benefit to the participants. | Res Soc Work Pract | 2022 | | CORD-19 |
| 6518 | Military Responses to the COVID-19 Pandemic Crisis in Latin America: Military Presence, Autonomy and Human Rights Violations The military in Latin America has been extensively involved in pandemic relief operations. This paper analyses the impact of militarization of pandemic relief operations on human rights. It argues that not all militarization is equally harmful to individuals in the region. When troops assume responsibilities regarding medical care and logistical support, human rights violations do not follow. When involved in policing the stay-at-home orders, the extent of human rights violations is explained by the level of operational autonomy the military has in public security operations. The more autonomous the military, more likely abuses are to occur. Additionally, military exposure to judicial prosecution for human rights offenses contributes to the explanation. After gathering original empirical evidence from 14 Latin American democracies on military presence in pandemic relief, we draw our inferences from process tracing on four comparative case studies of Argentina, Brazil, Chile, and El Salvador. | Armed Forces Soc | 2022 | | CORD-19 |
| 6519 | Development of a computer-aided tool for detection of COVID-19 pneumonia from CXR images using machine learning algorithm The novel coronavirus (SARS-CoV-2) is spreading rapidly worldwide, and it has become a greater risk for human beings. To curb the community transmission of this virus, rapid detection and identification of the affected people via a quick diagnostic process are necessary. Media studies have shown that most COVID-19 victims endure lung disease. For rapid identification of the affected patient, chest CT scans and X-ray images have been reported to be suitable techniques. However, chest X-ray (CXR) shows more convenience than the CT imaging techniques because it has faster imaging times than CT and is also simple and cost-effective. Literature shows that transfer learning is one of the most successful techniques to analyze chest X-ray images and correctly identify various types of pneumonia. Since SVM has a remarkable aspect that tremendously provides good results using a small data set thus in this study we have used SVM machine learning algorithm to diagnose COVID-19 from chest X-ray images. The image processing tool called RGB and SqueezeNet models were used to get more images to diagnose the available data set. Our adopted model shows an accuracy of 98.8% to detect the COVID-19 affected patient from CXR images. It is expected that our proposed computer-aided detection tool (CAT) will play a key role in reducing the spread of infectious diseases in society through a faster patient screening process. | N/A | 2022 | | CORD-19 |
| 6520 | Posición prono en respiración espontánea: una lección más del COVID-19 Con la pandemia se implementaron diversas estrategias para evitar la intubación y la ventilación mecánica invasiva. La posición prona (PP) tiene claros efectos benéficos en mejorar oxigenación por diversos mecanismos al tiempo que genera cambios hemodinámicos que pueden optimizar la función del ventrículo derecho. La evidencia de la PP en pacientes con síndrome de dificultad respiratoria aguda (SDRA) en ventilación mecánica invasiva (VMI) es contundente y obliga a considerarla en las primeras 24 horas de pacientes con PaO2/FiO2<150. La posición prona en respiración espontánea (PPRE) puede mejorar la oxigenación en pacientes con falla respiratoria e implementada mediante un protocolo que incluye una adecuada selección de pacientes puede evitar la intubación de pacientes en falla respiratoria. La presente revisión resume los antecedentes históricos, las bases fisiológicas de la posición prono en el paciente despierto, así como la evidencia que evalúa su aplicación en el paciente con COVID-19 al tiempo que resume el protocolo y la experiencia de un centro con esta estrategia como propuesta para estudios multicéntricos. With the pandemic, various strategies were implemented to avoid intubation and invasive mechanical ventilation. The prone position (PP) has clear beneficial effects in improving oxygenation by various mechanisms while generating hemodynamic changes that can optimize the function of the right ventricle. The evidence of PP in patients with acute respiratory distress syndrome (ARDS) on invasive mechanical ventilation (IMV) is overwhelming and makes it necessary to consider it in the first 24 hours in patients with PaO2 / FiO2 <150. The prone position in spontaneous breathing (PPRE) can improve oxygenation in patients with respiratory failure and implemented through a protocol that includes an adequate selection of patients can avoid intubation of patients in respiratory failure. This review summarizes the historical antecedents, the physiological bases of the prone position in the awake patient, as well as the evidence that evaluates its application in the patient with COVID-19 while summarizing the protocol and the experience of a center with this strategy. as a proposal for multicenter studies. | N/A | 2022 | | CORD-19 |
| 6521 | COVID-19-Impact of the lockdown on the weight variation among the Lebanese population The aim of this study is to assess lifestyle changes along with weight fluctuations during the COVID-19 lockdown in Lebanon. This cross-sectional study was conducted using a web-survey disseminated through social media platforms to a large sample of the Lebanese population between May 25th and June 8th, 2020, during the lockdown in Lebanon. Behavioral changes and weight variation during the confinement were assessed. 2,161 participants (64.9% female) aged 18 to 78 years old were included in this study. On average, no net weight variation was reported by the participants. 59.3% of the smokers changed their smoking habits, 40.7% of the drinkers reported a decrease in alcohol consumption, 43.5% of the participants exercised less than one time weekly and 35.8% changed their diet. Increased frequency of physical activity, following a diet during lockdown, decreased weight dissatisfaction (p<0.0001 for the 3 variables) were retained as significant factors associated with weight loss. Planning to engage in physical activity post lockdown was associated with weight gain (p=0.021). In the Lebanese population, no net weight variation was reported during the lockdown. Increasing physical activity and initiating diet were associated with weight loss. Healthcare authorities should be alerted about the importance of these factors during the follow-up of the confined population. | N/A | 2022 | | CORD-19 |
| 6522 | Pulmonary hematoidin deposition in a case of severe COVID-19 pneumonia A 59-year-old male with past medical history significant for hypertension, coronary artery disease, atrial fibrillation, hyperlipidemia, obesity, obstructive sleep apnea and deep vein thrombosis developed severe COVID19 pneumonia. His clinical course was noted for progressive respiratory failure that subsequently resulted in bilateral lung transplantation. Examination of the explanted lungs was notable for the presence of extensive grossly apparent bright yellow discolorations that histologically represented hematoidin deposits. The background lung was affected by diffuse alveolar damage, accompanied by infarcts and organizing thrombi. This case suggests that a combination of acute lung injury and thrombotic complications in severe COVID19 pneumonia can facilitate formation of pockets of anoxic environment leading to hematoidin deposition within lung tissue. | N/A | 2022 | | CORD-19 |
| 6523 | Mediating effects on the relationship between perceived service quality and public library app loyalty during the COVID-19 era The demand for using library apps to search for information has been increasing after the COVID-19 outbreak. To look into how the pandemic affects the users’ perception of the loyalty of using library apps, we designed this research by amalgamating the updated IS success model and S–O-R model to evaluate the service quality of a public library app under the Hong Kong Government mobile applications initiative. A third-order model is established to demonstrate the multi-faceted aspects of service quality and mediating effects of perceived brand image, satisfaction, and e-word of mouth. Using structural equation modeling, data collected from Hong Kong, a metropolis where mobile services empower its citizens, showed the interrelationships among service quality and possible outcomes (i.e., perceived brand image, user satisfaction, e-word of mouth, and user loyalty). Findings also indicate that the influence of perceived service quality on user loyalty could only be achieved through perceived brand image and user satisfaction. This is a timely study during the COVID-19 pandemic, as the lockdown and social distancing arrangements created challenges for citizens to search for information in public libraries in person. Our findings and suggestions reiterate the importance of considering the usability concepts when analyzing the service quality of each unique app. They also provide insights for practitioners in developing the next generation of apps for smart public information services and call for further investigation into the proposed hierarchical model and other potential factors related to service quality. | N/A | 2022 | | CORD-19 |
| 6524 | Nasopharyngeal COVID-19 Testing-Simple as ABC(SF Leak)? Introduction: Routine nasopharyngeal swabbing for Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) testing for SARS-COV-2 (COVID-19) has become the recommended test for safely delivering both emergency and elective patient care. To date over 256 million tests have been conducted in the UK. Whilst the advantages of routine COVID-19 swabbing are evident, it is important to acknowledge the associated common complications as well as unusual ones such as a Cerebrospinal Fluid (CSF) Leak. Methods: We report a case of a 69-year-old female who underwent nasopharyngeal swabbing in preparation for routine elective surgery. At the 8-week follow up the patient complained of a runny nose, which was positive for Beta-2 Transferring thus confirming a CSF leak. The likely area of concern for the CSF leak was in the region of the left fovea ethmoidalis where the bone was extremely thin with a solitary fluid filled air cell. The patient did later report right eye surgery 2 years previously which resulted in postoperative ethmoidal sinusitis managed with antimicrobials. This may have predisposed her to the CSF leak. Results: Nasal swabbing has been shown to be the cause of a CSF leak in a handful of cases, only four thus far have been reported in the literature. This rare but important complication has a significant morbidity with risk of meningitis reaching 19 % in some reports. Conclusions: It is the author’s intention to raise awareness of CSF leak as a potential complication of COVID19 Swabbing to ensure these are recognised promptly and managed in a timely manner. | Br J Oral Maxillofac Surg | 2022 | | CORD-19 |
| 6525 | Telephone consultations for skin cancers during COVID-19 Introduction: Within Crosshouse hospital, as a result of COVID19, we are trying to limit footfall by managing patients over telephone, if deemed appropriate. It was highlighted that referrals from allied HCPsfor urgent/non-urgent skin lesions may fall under the category of consultations which could be carried out by DCTs over telephone, in order to reduce the number of visits required for each patient. Methods: A questionnaire was completed by fellow DCT colleagues to assess how comfortable they are at ensuring all the required information is obtained during telephone consultations, and if they felt there was any way the consistency and quality of these could be improved. Results: Our fellow DCT colleagues expressed that they had had little training with regards to skin cancers in previous posts and felt that by carrying out teaching on relevant topics their confidence would be increased. With regards to improving the consistency of consultations, it was highlighted that a proforma would be beneficial. Conclusions: Following intervention; a further questionnaire was distributed which showed that by inclusion of these teaching topics, as well as a structured proforma, confidence had improved greatly. This also ensures that patients are receiving the best possible care during the COVID19 pandemic, and cancer patients can continue to be listed for procedures in a more streamlined approach. Although this transition during the COVID-19 period creates opportunities for flexibility, it also highlights important training needs that will need consideration as the impact of this pandemic on health services may continue for years. | Br J Oral Maxillofac Surg | 2022 | | CORD-19 |
| 6526 | Seven educational affordances of virtual classrooms For many teachers, the COVID-19 pandemic meant an instant shift from teaching in traditional to a virtual classroom to reduce the spread of infection. It represents a widespread and intensive case of digitalization of teaching practice and many stakeholders are asking the imminent question of which transformations that ‘will stick’ and become a constant in the ‘new normal’ onwards. However, research of online teaching in a high school context remains limited. In this study, we analyze what happens when teaching is redirected from the traditional to the virtual classroom and explore what characterizes educational affordances in the virtual classroom. The context is 15 high schools in Sweden and the empirical data includes a survey with a total of 1103 teachers. Educational affordances are used as an analytic lens to conceptualize what teaching activities that the virtual classroom afford. The main contribution includes theorizing about what activities, interactions, and procedures that the virtual classroom affords by presenting seven educational affordances and contrast these with teaching in traditional classrooms. The affordances consist of 1) Structure 2) One-to-one communication 3) Formalized reconciliations 4) Peace and quiet 5) Hidden back channels 6) Right time and 7) Reaches certain students. The seven affordances can make a foundation for reflection and discussions of how to create a didactic design adapted for different classrooms. Furthermore, we contribute with implications to teachers and school leaders. | N/A | 2022 | | CORD-19 |
| 6527 | Forthcoming Issues | Infect Dis Clin North Am | 2022 | | CORD-19 |
| 6528 | High-Coverage Nucleic Acid Probes for Distinguishing SARS-COV-2 from Influenza | Biophys J | 2021 | | CORD-19 |
| 6529 | Digital Educational Resources in Sciences for Visual Impaired Students in Times of COVID-19 | Biophys J | 2021 | | CORD-19 |
| 6530 | Factors that Affect the Binding of the N-Terminal Helix of Human ACE2 to Spike Protein of SARS-CoV-2 | Biophys J | 2021 | | CORD-19 |
| 6531 | Strategies for Enhancing Remote Biophysical Education: Development of a Module Based Training Series | Biophys J | 2021 | | CORD-19 |
| 6532 | Response in Immune Repertoires | Biophys J | 2021 | | CORD-19 |
| 6533 | Amplification-Free Detection of Viruses in Minutes using Single-Particle Imaging and Machine Learning | Biophys J | 2021 | | CORD-19 |
| 6534 | Binding Mode of SARS-CoV-2 Fusion Peptide to Human Cellular Membranes | Biophys J | 2021 | | CORD-19 |
| 6535 | [Translated article] Decline of Tuberculosis Rates and COVID-19 Pandemic. Fact or Fiction? | Arch Bronconeumol | 2022 | | CORD-19 |
| 6536 | Abstracts from Trainee Research Event 4th November 2021: Making the Most of Opportunities in. | Ulster Med J | 2022 | | CORD-19 |
| 6537 | Meeting Report: Aging Research and Drug Discovery Aging is the single largest risk factor for most chronic diseases, and thus possesses large socioeconomic interest to continuously aging societies. Consequently, the field of aging research is expanding alongside a growing focus from the industry and investors in aging research. This year’s 8th Annual Aging Research and Drug Discovery (ARDD) meeting was organized as a hybrid meeting from August 30th to September 3rd 2021 with more than 130 attendees participating on-site at the Ceremonial Hall at University of Copenhagen, Denmark, and 1800 engaging online. The conference comprised of presentations from 75 speakers focusing on new research in topics including mechanisms of aging and how these can be modulated as well as the use of AI and new standards of practices within aging research. This year, a longevity workshop was included to build stronger connections with the clinical community. | Aging (Albany NY) | 2022 | | CORD-19 |
| 6538 | Developing drugs against essential proteins of SARS-CoV-2 for the treatment of COVID-19 | Biophys J | 2022 | | CORD-19 |
| 6539 | Preparation of SARS-CoV-2 VLP to study viral assembly, egress and entry | Biophys J | 2022 | | CORD-19 |
| 6540 | Fusion peptide from SARS-2 spike transforms into a wedge inserted in a bilayer leaflet and thins the opposite leaflet | Biophys J | 2022 | | CORD-19 |
| 6541 | The role of virus geometry and matrix proteins in envelope and host membrane fusion | Biophys J | 2022 | | CORD-19 |
| 6542 | Development of a SARS-CoV-2 virus-like particle that performs as a direct cell entry reporter | Biophys J | 2022 | | CORD-19 |
| 6543 | A high throughput method for ensemble antibody affinity measurements for SARS-CoV-2 samples | Biophys J | 2022 | | CORD-19 |
| 6544 | "Locking on" to the early stages of the virus-cell interaction with active-feedback microscopy | Biophys J | 2022 | | CORD-19 |
| 6545 | SARS-Cov-2 variants of concern decelerate the dynamics of spike open conformation as an evolutionary strategy | Biophys J | 2022 | | CORD-19 |
| 6546 | Differential interactions between human ACE2 and spike RBD of SARS-CoV-2 variants of concern | Biophys J | 2022 | | CORD-19 |
| 6547 | Urgent computing and fair sharing of molecular-level structure and dynamics in COVID times | Biophys J | 2022 | | CORD-19 |
| 6548 | SARS-CoV-2 spike binding to ACE2 is stronger and longer ranged with glycans | Biophys J | 2022 | | CORD-19 |
| 6549 | Direct imaging of RNA loaded lipid-nanoparticles' self assembly and cellular expression for cancer immunotherapy and RNA-based vaccines | Biophys J | 2022 | | CORD-19 |
| 6550 | Characterizing the roles of chemo-mechanical couplings in the differential behavior of SARS-CoV-1 and SARS-CoV-2 spike glycoprotein | Biophys J | 2022 | | CORD-19 |
