This version of BIP! Finder aims to ease the exploration of COVID-19-related literature by enabling ranking articles based on various impact metrics.
Last Update: 18 - 01 - 2023 (628506 entries)
Popularity: Citation-based measure reflecting the current impact.
Influence: Citation-based measure reflecting the total impact.
Reader Attention: The current number of Mendeley readers.
Social Media Attention: The number of recent tweets related to this article.
*More details on these impact measures can be found here.
Exceptional score (in top 0.01%).
Substantial score (in top 1%).
Average score (in bottom 99%).
Score not available.
CORD-19 dataset(1) (list of papers)
LitCovid hub(2) (list of papers)
PMC & PubMed (citations)
Mendeley (number of readers)
COVID-19-TweetIDs(3) (tweets)
| Title | Venue | Year | Impact | Source | |
|---|---|---|---|---|---|
| 5501 | El liderazgo transformacional en los profesionales de la salud en tiempos de emergencia sanitaria | N/A | 2022 | CORD-19 | |
| 5502 | Coupling with COVID: The Role of Dyadic Coping in Relationship Satisfaction and Psychological Distress during the COVID-19 Pandemic Models of dyadic coping suggest that facing a stressful situation, such as the COVID-19 pandemic, with one’s partner to meet their needs is associated with positive outcomes. This study explored dyadic coping and its association with relationship satisfaction and distress in the time of the COVID-19 pandemic. Data were collected online from 564 participants. Participants completed measures of dyadic coping, relationship satisfaction, COVID anxiety, and OCD, and asked to describe their experience in an open-ended question. Results showed that experiences were quite polarized. Significant gender differences and differences for couples with/without children were noted for distress and relationship satisfaction. There was a significant interaction between dyadic coping and relationship satisfaction for women when predicting COVID OCD; however, post-hoc analysis showed that this interaction was only significant for women with children. The potential exponential burden that female couple members may face during COVID-19 as well as implications for intervention, are discussed. | J Fam Issues | 2022 | CORD-19 | |
| 5503 | Profiling temporal learning interests with time-aware transformers and knowledge graph for online course recommendation Profiling users’ temporal learning interests is key to online course recommendation. Previous studies mainly profile users’ learning interests by aggregating their historical behaviors with simple fusing strategies, which fails to capture their temporal interest patterns underlying the sequential user behaviors. To fill the gap, we devise a recommender that incorporates time-aware Transformers and a knowledge graph to better capture users’ temporal learning interests. First, we introduce stacked Transformers to extract users’ temporal learning interests underlying users’ course enrollment sequences. In addition, we design a time-aware positional encoding module to consider the enrollment time intervals between courses. Third, we incorporate a knowledge graph to utilize the latent knowledge connections between courses. The proposed method outperforms state-of-the-art baselines for course recommendation. Furthermore, findings in the ablation study offers several insights for future research. The proposed model can be implemented in online learning platforms to increase user engagement and reduce dropout rate. | N/A | 2022 | CORD-19 | |
| 5504 | Carceral ethnography in a time of pandemic: Examining migrant detention and deportation during COVID-19 Each year the United States government detains and deports hundreds of thousands of people who prior to their removal are held in confinement for an average of 55 days. The short and long-term effects of the coronavirus pandemic on migrant detention and deportation continue to be evaluated in real time, including how we can best study it. This paper provides a timely analysis on the relationship between immigration enforcement and confinement, public health emergencies, and ethnographic methods. It makes two contributions. The first is methodological and focuses on the challenges and opportunities of ethnographic methods in carceral settings when pandemic-related protocols have raised additional challenges to conventional in-person prison ethnography. The second contribution is empirical and documents how we adapted ethnographic methods to an interdisciplinary research design and to the exigencies of the pandemic to study the spread of the coronavirus in four immigrant detention facilities in New Jersey, USA. | Ethnography | 2022 | CORD-19 | |
| 5505 | The safe evacuation of persons from a building operating within COVID-19 restrictions Buildings’ environmental conditions were changed drastically around the world due to the COVID-19 pandemic hazards and restrictions. New social distance rules and organizational changes in the buildings appeared to require a modified fire safety evacuation analysis. The total number of building users under the revised requirements was often limited. Some additional restrictions, such as the reduction of evacuation exit availability, could cause escape problems in the case of fire. In order to determine how the pandemic restrictions could influence the evacuation conditions, a sports hall building was used to assess the impact of the restrictions on evacuation strategies. The research covered test evacuation simulations using the ‘Pathfinder’ modelling software, as well as manual calculations of the expected evacuation time. It was found that the pandemic social distance requirements could cause adverse evacuation conditions in the case of fire. The research helped formulate a simple mathematical algorithm for determining safety evacuation parameters under pandemic restrictions. PRACTICAL APPLICATION: The surrounding conditions for new buildings are driven by the reduction of social distances imposed by the COVID-19 pandemic. It has been found that pandemic social distancing can significantly extend the time of the evacuation of people. This article proposes a new simple mathematical algorithm for determining the evacuation parameters under pandemic restrictions, which allows the estimation of the required minimum width of emergency exits. This is a practical tool for those responsible for ensuring safety in buildings. | Build Serv Eng Res Technol | 2022 | CORD-19 | |
| 5506 | Relationship-based practice and digital technology in child and family social work: Learning from practice during the COVID-19 pandemic Vital services provided by social workers to children in care or on the edge of care were largely delivered “online” during the COVID-19 pandemic. This paper explores the potential impact of these changes on vulnerable children and their families. Relationship-based practice is integral to social work and the shift to digital communication during the COVID-19 pandemic has led to accelerated practice changes and implications for relationship building both with and between service users. Going forward, social workers and other professionals are likely to move to an increasingly hybrid model of communication, combining both digital and face-to-face methods. This article identifies the impact of digital communication on relationships in professional practice, drawing on three studies of digital communication in the UK carried out at the University of East Anglia. The first considered how child protection social workers responded to the challenges of COVID-19, the second looked at how children in care were keeping in touch with their birth families and the third focused on the approaches being taken to moving children from foster care to adoptive families. Five themes related to relationships were identified across all three studies: the significance of the age and developmental stage of the child; the frequency of contact and communication; digital literacy/exclusion; the impact of the lack of sensory experience; and the importance of the relationship history. The article concludes with implications for utilising digital methods in building and maintaining relationships in practice and highlights the need to consider both the inner and outer worlds of those involved. | Dev Child Welf | 2022 | CORD-19 | |
| 5507 | Academia During the Time of COVID-19: Examining the Voices of Untenured Female Professors in STEM This paper highlighted the diverse voices of 84 female-identifying professors in STEM fields who responded to a series of open-ended questions regarding work, family, and tenure experiences in the context of the current global pandemic. The current paper is part of a longitudinal study of the vocational experiences of tenure-track women in STEM that has examined the “leaky pipeline” in women’s academic careers. Consensual Qualitative Research-Modified (CQR-M; ) was implemented to analyze the data. The findings suggested that participants perceived the precarious balance between work and family to have increased in difficulty in the face of COVID-19. Among untenured female faculty with children, an added layer of challenge was noted related to loss of childcare in the wake of the pandemic. The pre-existing, pervasive barriers (i.e., institutional, systemic, and psychological) were further exacerbated by familial barriers for female STEM faculty seeking tenure during COVID-19. Overall, the results indicated missed opportunities within higher education to implement supportive policies for untenured female faculty in STEM. Clinical implications, future research directions, and social advocacy interventions in the context of COVID-19 are discussed. | J Career Assess | 2022 | CORD-19 | |
| 5508 | CEBIT screening for inhibitors of the interaction between SARS-CoV-2 spike and ACE2 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, causing COVID-19, is the most challenging pandemic of the modern era. It has resulted in over 5 million deaths worldwide. To quickly explore therapeutics for COVID-19, we utilized a previously-established system, namely CEBIT. We performed a high-throughput screening of FDA-approved drugs to inhibit the interaction between the receptor-binding domain (RBD) of SARS-CoV-2 spike proteinand its obligate receptor ACE2. This interaction is essential for viral entry and therefore represents a promising therapeutic target. Based on the recruitment of interacting molecules into phase-separated condensates as a readout, we identified six positive candidates from a library of 2572 compounds, most of which have been reported to inhibit the entry of SARS-CoV-2 into host cells. Our surface plasmon resonance (SPR) and molecular docking analyses revealed the possible mechanisms via which these compounds interfere with the interaction between RBD and ACE2. Hence, our results indicate that CEBIT is highly versatile for identifying drugs against SARS-CoV-2 entry, and targeting CoV-2 entry by small molecule drugs is a viable therapeutic option to treat COVID-19 in addition to commonly used monoclonal antibodies. | N/A | 2022 | CORD-19 | |
| 5509 | Effects of the COVID-19 pandemic on SCUBA diving experience in marine protected areas Faced with the need for isolation of most people to reduce the transmission of COVID-19, a great concern for the well-being of the population has resurfaced. Considering the numerous benefits of outdoor activities to human health and well-being, we assessed whether the quality of the experience of recreational divers in a marine protected area (MPA) was impacted during the pandemic. We applied a semi-structured questionnaire to divers, collected their socioeconomic profile, preferences, motivations, experiences, and compared the results with those obtained in the previous season. We found that the quality of the recreational diver's experience remained high even during one of the world's biggest health crises. This suggests that the combination of contact with a preserved environment and the adaptation of regulations in favor of visitor safety was enough to stimulate positive experiences. Therefore, we highlight the importance of investing in adaptive management so that MPAs continue to promote ecosystem services such as human health and subjective well-being. | N/A | 2022 | CORD-19 | |
| 5510 | Pulling back the curtains: the realities and complexities of juggling parenthood and a career in academia: Kerry F. Crawford and Leah C. Windsor, The PhD Parenthood Trap: Caught Between Work and Family in Academia, Georgetown University Press, 2021 | High Educ (Dordr) | 2022 | CORD-19 | |
| 5511 | Theme-based Book Review: public policy problems and solutions? This theme-based book review considers three recent titles related to public policy problems, processes, and solutions, from scholarly and practitioner perspectives: The Political Formulation of Policy Solutions, edited by Philippe Zittoun, Frank Fischer, and Nikalaos Zahariadis; A Guidebook for City and County Managers: Meeting Today’s Challenges, by James M. Bourey; and Solving Public Problems: A Practical Guide to Fix Our Government and Change Our World, by Beth Simone Noveck. | N/A | 2022 | CORD-19 | |
| 5512 | Profesionales de la primera línea: desafíos en su formación universitaria | N/A | 2022 | CORD-19 | |
| 5513 | The collateral damages of lockdown policies: A review of the "The Great Covid Panic" by Paul Frijters, Gigi Foster and Michael Baker | J Behav Exp Econ | 2022 | CORD-19 | |
| 5514 | Coping with and challenging the impacts of COVID-19 | Lancet Child Adolesc Health | 2022 | CORD-19 | |
| 5515 | Safety of Air Medical Transport of Patients With COVID-19 by Personnel Utilizing Routine Personal Protective Equipment Background Air medical transport of patients with known or suspected COVID-19 likely represents a high-risk exposure to crewmembers as aircraft cabins are quite small resulting in very close personal contact. The actual risk to medical crewmembers is not known. Methods We conducted an IRB-exempt, retrospective study of air medical transport of patients with known or suspected COVID-19 by eight programs in the Four Corners Region to determine the number of symptomatic COVID-19 among air medical crew members compared to total exposure time. All programs utilized similar routine PPE including N-95 masks and eye protection. Total exposure time was considered from time of first patient contact until hand-off at a receiving hospital. Results There were 616 air transports: 62% by fixed-wing and 38% by rotor-wing aircraft between March 15th and September 6th 2020. 407 patients (66%) were confirmed COVID+ and 209 (34%) were under investigation. Patient contact time ranged from 38 to 432 minutes with an average of 140 minutes. The total exposure time for medical crew was 2,924 hours; exposure time to confirmed COVID+ patients was 2008 hours. Only 30% of patients were intubated, the remainder had no oxygen (8%), low flow nasal cannula (42%), mask (11%), high-flow nasal cannula (4.5%) and CPAP or BPAP (3.5%). Two flight crew out of 108 developed COVID that was presumed related to work. Conclusions Air Medical Transport of patients with known or suspected COVID-19 utilizing routine PPE is remarkably safe for medical crew members, even when patients are not intubated. This has implications for healthcare personnel in any setting that involves care of patients with COVID-19 in similarly confined spaces. | Air Med J | 2022 | CORD-19 | |
| 5516 | Processing strategies to improve the breadmaking potential of whole-grain wheat and non-wheat flours Strategies to increase the bio-functionality of staple food, such as bread, by incorporating whole-grain wheat flour or flour from other, non-wheat grains instead of refined wheat flour are often constrained with the lack of their techno-functionality, despite the associated beneficial effect on consumers' health and well-being. Most of the available studies investigating the possibilities to improve technological and sensory quality of bread prepared using whole-grain wheat and non-wheat flours still rely on formulation approaches in which different additives and novel ingredients are used as structuring agents. Less attention has been given to technological approaches which could be applied to induce structural changes on biopolymer level and thus increase the breadmaking potential of whole grains such as: modification of grain and biopolymers structure by germination, flour particle size reduction, dry-heat or hydrothermal treatment, atmospheric cold plasma, high-pressure processing or ultrasound treatment. Strategies to modify processing variables during breadmaking like dough kneading and hydration modification, sourdough fermentation or non-conventional baking techniques application are also poorly exploited for bread preparation from non-wheat grains. In this paper, the challenges and opportunities of abovementioned processing strategies for the development of bread with whole-wheat flours and non-wheat flours from underutilised gluten-containing or gluten-free cereals and pseudocereals will be reviewed throughout the whole breadmaking chain: from grain to bread and from milling to baking. Feasibility of different strategies to increase the technological performance and sensory quality of bread based on whole-grain wheat flours or flours from other, non-wheat grains will be addressed considering both the environmental, safety and nutritive advantages. | N/A | 2022 | CORD-19 | |
| 5517 | Technostress from Smartphone Use and Its Impact on University Students' Sleep Quality and Academic Performance Smartphone has been widely used by the younger generation. However, research exploring the technostress triggered by smartphone use lacks. Based upon the stressor-strain-outcome model, this study examined how smartphone use, especially compulsive use, life invasion, and information overload, cause university students’ technostress and, furthermore, how technostress impact their sleep quality and academic performance. Data were collected from 540 undergraduates studying at a Chinese public university and analyzed using structural equation modeling. Results revealed that compulsive smartphone use and information overload are both positively associated with technostress, which in turn have a positive effect on poor sleep quality and academic self-perception. Furthermore, compulsive smartphone use indirectly predicts sleep and academic problems through the mediating effect of technostress. The findings contribute to extend the existing technostress literature and provide valuable practical implications for smartphone-related designers, university teachers, and students. | N/A | 2022 | CORD-19 | |
| 5518 | Islamic Stock indices and COVID-19 pandemic Motivated by the COVID-19 pandemic, we construct a single factor predictive model for stock returns that incorporates uncertainty index for pandemics and epidemics (UPE). Specifically, we examine whether Islamic stocks are either vulnerable or have better hedge potential when compared to the performance of their conventional counterparts. In general, we find that the Islamic stocks can be used to hedge whereas the conventional stocks are seen to be vulnerable to uncertainty due to pandemics across different time periods. In particular, during COVID-19 pandemic, although the hedging effectiveness of Islamic stock seems to decline, it is still better compared to the worse performance of the conventional stocks. The outcome remains the same even after controlling our model for oil price, geopolitical risk and economic policy uncertainty. We further evaluate the predictive power of the UPE both for the in-sample and out-of-sample periods by comparing its forecast performance with that of a benchmark model. Our results suggest that the consideration of the UPE information in the valuation of stocks is crucial for investment decisions. | N/A | 2022 | CORD-19 | |
| 5519 | [Translated article] RF-SARS-CoV-2 Vaccination and Immunotherapy in Dermatology | Actas Dermosifiliogr | 2022 | CORD-19 | |
| 5520 | Selection of most effective COVID-19 virus protector using a novel MCGDM technique under linguistic generalised spherical fuzzy environment In this article, we have introduced a new linguistic generalized spherical fuzzy set by combining the idea of generalized spherical fuzzy set and linguistic fuzzy set. Linguistic generalized spherical fuzzy set is described by linguistic positive, linguistic neutral and linguistic negative membership degrees with the condition that the square sum of its linguistic membership degrees is less than or equal to 3 which deal with the uncertain and imprecise information in decision making in a much more suitable way. We have discussed some basic operations of linguistic generalized spherical fuzzy sets and introduced new score and accuracy functions to compare any two linguistic generalized spherical fuzzy numbers. We have developed various types of aggregation operators based on the newly defined linguistic generalized spherical fuzzy set, which have been manifested to construct a new multi-criteria group decision-making technique. Numerical example has been presented to demonstrate the proposed model. Finally, sensitivity and comparative analysis is performed to show the reliability and efficiency of the new multi-criteria group decision-making technique. | N/A | 2022 | CORD-19 | |
| 5521 | Synthesis, Properties and Biological Activity of Poly(1-vinyl-1,2,4-triazole) and Silver Nanocomposites Based on It The review summarizes the data on the synthesis, physicochemical properties, and biological activity of poly(1-vinyl-1,2,4-triazole) and its nanocomposites with silver nanoparticles. The results of studying the antibacterial and antitumor activity of the polymers and nanocomposites and their immunomodulatory ability, toxicity, and interaction with body cells, as well as the prospects for their use in the development of medical materials, are presented. | N/A | 2022 | CORD-19 | |
| 5522 | A Review on Si-Based Ceramic Matrix Composites and their Infiltration Based Techniques This review paper aims to look at silicon-based ceramic matrix composites and infiltration-based approaches for them. There are many different types of infiltration-based manufacturing processes, each with its own set of features. The best technique is chosen depending on the needs and desired attributes. With these considerations in mind, any type of infiltration might be selected to meet the requirements. Silicon-based ceramics has been highly used in the fields of aerospace, medical, automobile, electronics, and other various industries so it is important to study about their applications as well. This review outlines the evolution of composites from early 7000 BCE to composites today and discussed about various infiltration techniques for manufacturing silicon based ceramic matrix composites. This article also gives the comprehensive review of general characteristics and mechanical properties of silicon-based composites used in a variety of engineering sectors. The application section entails the wide range of engineering fields with consideration of infiltration techniques, which would be helpful for researchers to study and correlate the different infiltration techniques for end applications. | N/A | 2022 | CORD-19 | |
| 5523 | Way out of the one-way? Effects of the COVID-19 pandemic on the generation of waste from packaging in Germany | N/A | 2022 | CORD-19 | |
| 5524 | An analysis of the blockchain and COVID-19 research landscape using a bibliometric study The scientific community has become concerned about the impact of blockchain technology as a motivational tool in the COVID-19 era. Since the beginning of the pandemic, the number of scientific articles published in this field has been increasing, making it highly desirable to carry out a bibliometric study to identify research efforts. Therefore, the aim of this work was to conduct a literature review of blockchain and COVID-19 technology in the field of Business Management to identify recent lines of research. To do so, we used a text mining technique on a corpus composed of 37 articles in the Web of Science database. The results obtained clearly show 3 distinct clusters. The first represents the blockchain technology framework in organizations and stakeholders in which the research methodology in artificial intelligence is very important. The second shows the need to take into account business sustainability caused by COVID-19. The third indicates the impact of the pandemic on the supply chain industry. | N/A | 2022 | CORD-19 | |
| 5525 | COVID-Krise und Kinderrechte: Dogmen pandemiegemäßer Alternativlosigkeit auf dem Prüfstand COVID-19 und die Maßnahmen dagegen stellen auch die Soziale Arbeit besonders in punkto Kinderrechte vor neue und alte Herausforderungen. Massive Verletzungen der UN-Kinderrechtskonvention und ein Anstieg von Armut in kindlichen und jugendlichen Lebenslagen sind zu verzeichnen. Die Art und Weise der Pandemiebekämpfung war und ist nicht alternativlos (gewesen). Der Beitrag hebt hervor, dass die Kinderpolitik der Regierung über weite Strecken von Instrumentalisierung und Kapital-Konformismus, statt von Kinder-Gerechtigkeit gekennzeichnet war und ist. Das muss sich völkerrechts- und grundgesetzgemäß dringend ändern, indem der Kindeswohlvorrang sowie die Kinderrechte auf Schutz, Förderung und Beteiligung (endlich wieder) umgesetzt werden. | N/A | 2022 | CORD-19 | |
| 5526 | Informal Exercise of Power: Undermining Democracy Under the EU's Radar in Hungary and Poland Hungary and Poland have seen the most widespread erosion of democracy in the European Union since Fidesz and Law and Justice started their authoritarian remaking in 2010 and 2015, respectively. Despite the EU’s introduction of various doctrinal innovations, it could not force these regimes to comply with the core values of the EU. While the literature has focused on the formal violation of the rule of law, the links between informal power and the limited constraining role of the EU have remained undertheorized. This article aims to fill the gap by studying the informal exercise power of the Fidesz and PiS governments that helped them to create an uneven political playing field. Connecting the literature on hybrid authoritarian regimes and informality, it will be shown through three main domains how the Hungarian and Polish governments (1) distributed informal political-economic decision-making power informally throughout clientelist corruption, (2) captured the media through loyal oligarchs/allies, and (3) employed electoral clientelism to tilt the electoral playing field in their favor. While the study proposes a theoretical framework related to the Hungarian and Polish examples, it is also a warning for the EU to take the informal exercise of power seriously. | N/A | 2022 | CORD-19 | |
| 5527 | Review of Liz Jackson (2021). Beyond Virtue: The Politics of Educating Emotions: Cambridge, UK: Cambridge University Press. 250 pp. ISBN 9781108482134 (Hardcover) | N/A | 2022 | CORD-19 | |
| 5528 | Towards an Ambidextrous, Robust and Resilient Impact Assessment of Sustainable Smarter Specialisation Strategies (AR2IA/S4) ΤΑ ΠΑΝΤΑ ΡΕΙ. (Everything Flows, Heraclitus of Ephesus, 535–475BC). When the EU Framework Program designers and policy makers were creating the Horizon 2020 program, they could never imagine or anticipate that 2020 would turn out to be the ANNO HORIBILIS GLOBALIS due to COVID-19 depredations with socio-economic, socio-political and socio-technical impacts and implications for policies, practices and politics. In this paper, we provide an approach that builds on recent developments and insights based on efficacious multi-criteria approaches that leverage design thinking philosophies and agile methodologies. This is in order to achieve an ambidextrous, robust and resilient architecture of impact assessment of S3 and thus set the stage for the next generation of S3 that should be aptly framed as Sustainable (Triple Top and Bottom Line) Smarter (Efficacious) Specialisation Strategies (AR2IA/S4). In a more concrete manner, we identify and illustrate cases in the context of S3 formulation and implementation at the sectoral and regional levels where AR2IA could help engender S4 especially in the context of the pandemic disruptions so as to be better prepared and enabled to cope with such future challenges and identify within them endogenous opportunities. | N/A | 2022 | CORD-19 | |
| 5529 | Assessment of residual chlorine in soil microbial community using metagenomics Chlorine-containing disinfectants have been widely used around the world for the prevention and control of the COVID-19 pandemic. However, at present, little is known about the impact of residual chlorine on the soil micro-ecological environment. Herein, we treated an experimental soil-plant-microbiome microcosm system by continuous irrigation with a low concentration of chlorine-containing water, and then analyzed the influence on the soil microbial community using metagenomics. After 14-d continuous chlorine treatment, there were no significant lasting effect on soil microbial community diversity and composition either in the rhizosphere or in bulk soil. Although metabolic functions of the rhizosphere microbial community were affected slightly by continuous chlorine treatment, it recovered to the original status. The abundance of several resistance genes changed by 7 d and recovered by 14 d. According to our results, the chlorine residue resulting from daily disinfection may present a slight long-term effect on plant growth (shoot length and fresh weight) and soil micro-ecology. In general, our study assisted with environmental risk assessments relating to the application ofchlorine-containing disinfectants and minimization of risks to the environment during disease control, such as COVID-19. [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: Supplementary material is available in the online version of this article at 10.1007/s42832-022-0130-x and is accessible for authorized users. | N/A | 2022 | CORD-19 | |
| 5530 | Design Thinking Innovation Within the Quadruple Helix Approach: a Proposed Framework to Enhance Student Engagement Through Active Learning in Digital Marketing Pedagogy The purpose of this paper is to develop a framework for enhancing student engagement through active learning and design thinking workshops online. The COVID-19 pandemic has increased the need for digital engagement exponentially, yet the important experiences of collaborative and active learning (AL) have become more challenging to facilitate and support in circumstances of remote access during classes. As such, design thinking (DT) online presented a unique opportunity to explore this collaborative approach to engaging in user-centred design and design innovation. To explore a specific curriculum design dilemma and validate the methodology adopted, online DT workshops were conducted with two different cohorts of students toward co-creating more student-centred forms of learning in two digital marketing (DM) courses. The approach was guided by the POLARIS active learning framework to embed the framework’s seven perspectives (Purpose, Objectives, Learning landscape, Activities and assessment, Resources, Inter-relation with stakeholders, and Student engagement) which were considered to better enhance student engagement in an online learning environment. Using the framework proposed, which additionally integrates Quadruple Helix Model (QHM) actors, would facilitate further DT innovation towards co-creating new value in digital marketing pedagogy, curriculum design, and beyond. | N/A | 2022 | CORD-19 | |
| 5531 | Reliability of Virtual Physical Performance Assessments in Veterans during the COVID-19 Pandemic Research Objectives To determine the reliability of three physical performance tests performed via a telehealth visit (30-second arm curls test, 30-second chair stand test, 2-minute step test) among community-dwelling older Veterans. Design Cross sectional study. Setting Virtual. Participants Veterans (mean age 75) who enrolled in Gerofit, virtual group exercise program. Interventions N/A. Main Outcome Measures Participants were tested by two different assessors at one time point. The Interclass Correlation Coefficient (ICC) with 95% confidence intervals (CIs) and Bland-Altman plots were used as measures of reliability. To assess generalizability, ICCs were further evaluated by health conditions (type 2 diabetes, arthritis, obesity, and depression). Results Assessments were conducted among 55 participants. The ICC was above 0.98 for all three tests across health conditions and Bland-Altman plots indicated that there were no significant systematic errors in the measurement. Conclusions The virtual physical performance measures appear to have high reliability and the findings are generalizable across health conditions among Veterans. Thus, they are reliable for evaluating physical performance in older Veterans in virtual settings. Author(s) Disclosures The authors declare no conflict of interest. | Arch Phys Med Rehabil | 2022 | CORD-19 | |
| 5532 | Barriers to School and Work Transitions for Youth With and Without a Disability During The COVID-19 Pandemic: A Qualitative Comparison Research Objectives To explore barriers to school and work transitions for youth with and without a disability during the COVID-19 pandemic. Design An interpretive descriptive qualitative approach involving in-depth interviews. Setting Greater Toronto Area, Ontario, Canada which was considered a hot zone for COVID-19 cases and deaths. Participants A purposive sample of 35 youth (18 with a disability; 17 without), aged 16-29 (mean age 23). Interventions Not applicable. Main Outcome Measures Semi-structured interviews with participants. Results Our findings revealed several similarities and some differences between youth with and without disabilities regarding barriers to school and work transitions during the COVID-19 pandemic. Key themes related to these barriers involved: (1) difficult transition to online school and working from home (i.e., expense of setting up home office, technical challenges, impact on mental health), (2) uncertainty about employment (i.e., under-employment, difficult working conditions, difficulty finding work, disability-related challenges) and (3) missed career development opportunities (i.e., cancelled or reduced internships or placements, lack of volunteer opportunities, uncertainties about career pathway, longer-term impact of pandemic). Conclusions Our findings highlight that youth with disabilities may need further support in engaging in meaningful and accessible vocational activities that align with their career pathway. Author(s) Disclosures None. | Arch Phys Med Rehabil | 2022 | CORD-19 | |
| 5533 | Mental and Behavioral Health Needs of Transition Age Youth Experiencing Homelessness During the COVID-19 pandemic Research Objectives For the agencies interviewed, what were the best practices utilized for the behavioral and mental health issues in TAYEH before the COVID-19 pandemic? How has the COVID-19 pandemic affected TAYEH ability to access services and supports to address their behavioral and mental health needs? What programs/processes/procedures are being utilized now to assist TAYEH in the time of the COVID-19 pandemic? Design Qualitative Method were utilized to conduct a content analysis of the data collected via recorded virtual Interviews. Setting The study was conducted on a virtual platform focusing on multiple agencies across the United States. Participants Three organizations agreed to be interviewed, with four representatives being interviewed in total. Interventions There was no intervention. This was a qualitative content analysis. Main Outcome Measures Findings from the interviews indicated increased numbers of youth trying to access services during the pandemic. In addition, the agencies interviewed were seeing increased numbers of youth with mental and behavioral health issues, including substance abuse, PTSD, anxiety, and depression. Results The increase in need from TAYEH resulted in permanent services being added to their organization to help this population. The increase in need of services during the COVID-19 pandemic from TAYEH may have been due to limitations on the number of individuals allowed to occupy a space. It was agreed through the interviews that there could be ways to improve the services and resources for the behavioral needs of youth in their agencies. Conclusions Although there were challenges to accessing services like virtual meetings and staff illness, agencies developed strategies to meet the needs of the youth. These included creating virtual drop in centers and providing more telehealth services . Author(s) Disclosures None. | Arch Phys Med Rehabil | 2022 | CORD-19 | |
| 5534 | Visual dysfunction in survivors of COVID-19: Case series Research Objectives This case series aims to expand knowledge on COVID-19 diagnosis and functional vision status and highlight the importance of best practices with regards to comprehensive vision screening. Design Case Series. Setting Outpatient rehabilitation clinics in Minnesota, USA and Texas, USA. Participants Five adults admitted to rehabilitation with diagnosed post-acute sequelae of COVID-19, inclusive of visual dysfunction. Three participants had no remarkable history of visual dysfunction or acquired brain injury; two participants had prior neurological history: one with mild traumatic brain injury and one with concussion, both are significant for visual dysfunction following the acute events. Interventions All patients were treated in acute and outpatient rehabilitation settings following the positive visual screen. Main Outcome Measures N/A. Results This case series highlights visual dysfunction in five patients diagnosed with COVID-19, with and without prior history of neurological disorders. All five participants described newly acquired or a recrudescence of visual symptoms which impacted daily function. 5 out of 5 patients had confirmatory findings following comprehensive visual assessment. Visual symptoms consistent between the cases included, but were not limited to, blurred vision, diplopia, photophobia, impaired near-point focus, headaches, and general visual discomfort and asthenopia throughout their day. Conclusions Individuals diagnosed with COVID-19 present with a wide-range of symptoms and often neurological sequelae, without a predictable pattern. Despite the substantial impact of COVID-19 globally, and the massive increase in research efforts, certain domains remain poorly understood. One such domain is vision and the impact that visual impairment attributed to COVID-19 has on functional independence. This case series supports new evidence for visual sequelae in COVID-19 with and without history of a neurological disorder. Such findings motivate new research questions such as the pathophysiological differences between acute onset versus recrudesced visual dysfunction. It is imperative that consistent and comprehensive visual screening is performed for individuals who are diagnosed with COVID-19. Universal awareness of potential visual dysfunction following COVID-19 infection is essential for timely screening, referrals and treatment to optimize patient outcomes. Author(s) Disclosures There are no relevant author disclosures. | Arch Phys Med Rehabil | 2022 | CORD-19 | |
| 5535 | How People with a Chronic Health Condition Have Promoted their Health during COVID-19 Research Objectives To interview individuals with long-standing Multiple Sclerosis about their perceptions of COVID-19 restrictions on health, health care access, and health promotion. Design A descriptive qualitative approach with maximum variation sampling was used to facilitate low inference interpretation. After coming to consensus on the codes, the researchers clustered the codes and used them to identify emerging themes, consistent with analytic techniques suggested by Miles and Huberman. Setting Telephone interviews were conducted with individuals with multiple sclerosis living in the community who were recruited from the mailing list of the National MS Society. Participants The 24 individuals interviewed had an average age of 66 years, and had been diagnosed an average of 32 years. Half were married, and 75% were female. Many had college degrees; six were employed. Interventions This is a qualitative study with no intervention. Main Outcome Measures Self-reported health, health care access, and health promoting behaviors. Results Four interconnected themes emerged from the analysis: negative effects on health and health promotion, being isolated, loss of spontaneity in daily life, and resilience. Although most individuals initially reported no effect of COVID-19 on their health, additional probing revealed that some felt weaker and had more balance problems. Normal exercise regimens had been disrupted for approximately half of them. Several also described decreased social interactions; 80% expressed negative emotional impacts. Many utilized previously developed coping mechanisms, such as cognitive reframing, and support from family as they adapted to COVID-19. Most individuals reported no MS exacerbations and were able to have some contact with providers, usually through telehealth. Conclusions Providers and researchers should monitor the on-going impact of the COVID-19 pandemic on physical functioning and emotional well-being among individuals with MS. Higher levels of depression have been previously reported among those with MS. For those needing mental health supports, rapid advancements in telehealth enable providers to refer them to psychological services provided through access from their homes. Author(s) Disclosures The authors have no conflicts of interest to declare. | Arch Phys Med Rehabil | 2022 | CORD-19 | |
| 5536 | COVID-19 Impact on Delivery of Rehabilitation For Persons With Traumatic Brain Injury Research Objectives To describe how the COVID-19 pandemic influenced treatment practices for chronic pain in persons with traumatic brain injury (TBI) and facilitators and barriers to rehabilitation care. Design A descriptive, qualitative study. Setting Traumatic brain injury model systems (TBIMS) civilian and Veterans facilities. Participants The secondary analysis included providers consisting of rehabilitation therapists (physical therapists, speech language pathologists, and occupational therapists), medical doctors, nurses, clinical and neuro psychologists, and resource managers (n=63) for persons with TBI and chronic pain. Interventions N/A. Main Outcome Measures A semi-structured qualitative telephone interview consisted of 13 questions asking about treatment practices and facilitators and barriers to rehabilitation for people with TBI and chronic pain during the COVID-19 pandemic. Results The COVID-19 pandemic impacted treatment practice across civilian and VA TBIMS facilities. Thematic analysis revealed that the main changes to treatment practices were switching to virtual visits, the impact of COVID-19 precautions such as social distancing and wearing masks had on providing treatment, and in some cases, treatment was halted. Facilitators to care included improved communication between providers and their patients, the increase in use of telehealth to provide care, and increased access to providers. Barriers to rehabilitation care identified by mainly civilian providers included COVID-19 visitor restrictions on family involvement, and the lack of access patients had to their providers during this time, specifically with cancelled appointments or wait lists. Both civilian and VA providers described how COVID-19 logistics for cleaning and social distance impacted scheduling and the number of patients who could be seen. Conclusions The global COVID-19 pandemic served as a major disruptor to provision of healthcare. The switch from mainly in person care to the use of telehealth to deliver care was a major transition for providers and patients. Future research on the impact of telehealth on patient outcomes and when to use telehealth versus in person is needed. Author(s) Disclosures This work is supported by the National Institute on Disability, Independent Living, and Rehabilitation Research (90DPTB0017 and 90DPTB0008) and General Dynamics Health Solutions (W91YTZ-13-C-0015; HT0014-19-C-0004). | Arch Phys Med Rehabil | 2022 | CORD-19 | |
| 5537 | Implementation of Cognitive Telerehabilitation during COVID-19 Pandemic Objective(s) The purpose of this systematic review was to examine the effectiveness of implementing cognitive telerehabilitation during the Coronavirus pandemic. Data Sources This review was conducted using the following databases: Taylor & Francis, Science Direct, Google Scholar, and ProQuest Central. Inclusion criteria consisted of peer-reviewed articles published in English between the years of 2017-2021. Keywords for the search included cognitive telerehabilitation, pandemic, COVID-19, and Coronavirus. A total number of 17 articles were reviewed, and 6 articles were retained. Study Selection Literature Review. Data Extraction Independent extraction by multiple observers. Data Synthesis Research indicated that cognitive telerehabilitation was an effective modality for individuals with neurological conditions, including stroke, traumatic brain injury, Alzheimer's disease, Parkinson's disease and parkinsonian syndromes, and multiple sclerosis. Furthermore, reviewed literature reported that remote communication technologies can be effective options to support health care interventions, including cognitive rehabilitation. Conclusions Social distancing measures implemented during the COVID-19 pandemic interrupted access to routine medical care for many individuals with neurological diseases. Overall, studies indicated that cognitive telerehabilitation was an effective modality in neurorehabilitation as it overcame both geographical and social-distancing limitations. Moreover, methodological and technological improvements may improve the delivery of cognitive telerehabilitation for individuals with reduced mobility. New alternatives such as cognitive telerehabilitation may be implemented as an urgent and effective response to provide continuity of care and social connectedness during the COVID-19 pandemic. Author(s) Disclosures N/A. | Arch Phys Med Rehabil | 2022 | CORD-19 | |
| 5538 | Using Recreation for Rehabilitation Through an Adapted Community Bowling Program During COVID-19: A Pilot Study of Youth Outcomes Research Objectives To examine the effects of a community bowling program with COVID-19 protocols on quality of life and physical abilities in children with disabilities during the COVID-19 pandemic. Design Researchers retrospectively examined data collected by the community-based program. Data collection occurred pre and post participation in the community-based bowling program. Setting The study was conducted in four public bowling facilities within the general community. Participants Study participants included 34 adolescents and children who participated in a free community-based adapted bowling program. Interventions Children and adolescents who participated in the program bowled for one hour, once a week for six to twelve weeks. The duration of the bowling program varied according to the location hosting the program. Main Outcome Measures Quality of life was evaluated using the PedsQL: Pediatric Quality of Life Inventory Version 4.0 Parent Report for Children (ages 8 to 12). The PedsQL survey was completed pre- and post-program by the parents of the study participants. Participants also completed a pre- and post-program pinch strength test, a grip strength test, a trunk flexion test, and a shoulder range of motion measure. These tests were administered by physical therapy faculty and occupational therapy students. Results The subjects were thirty-four children and adolescents with various disabilities participating in a community bowling program. Autism Spectrum Disorder (ASD) was the most commonly reported condition among the study participants, present in 14 of 34 children (or 41%). There were significant improvements (p-value=0.01) in bilateral pinch and grip strength. No differences were found in thoraco-lumbar range of motion or shoulder range of motion. Significant improvements were found in quality of life (p-value=0.01) primarily related to social and emotional factors. Conclusions Adapted bowling had a positive effect on the QoL and physical skills of children/adolescents participating in a community-based program. The program was replicable across sites and there was no difference in outcomes from the newly established programs to the established programs. Author(s) Disclosures No conflicts of interest have been identified or reported by any of the researchers participating in this study. | Arch Phys Med Rehabil | 2022 | CORD-19 | |
| 5539 | Pressure Injury as Insidious Comorbidity in Ventilator-Dependent Respiratory Failure (VDRF) Secondary to COVID-19: A Case Report Research Objectives To highlight opportunities to decrease adverse outcomes in the acute management of COVID-19 infection. Design Descriptive single-subject study. Setting Inpatient/Acute rehabilitation. Participants A 47-year-old female with Ventilator-Dependent Respiratory Failure (VDRF) secondary to COVID-19. Interventions In the ED, Patient was started on antibiotics (azithromycin, ceftriaxone), nebulizer treatments, intravenous fluids, and intramuscular corticosteroids (methylprednisolone). On hospital admission, she was initiated on antiviral Remdesivir and received 1 unit of convalescent plasma. Self-proning was encouraged, yet Patient required progressive increase in oxygen (O2) supplementation. She was intubated from Hospital Day (HD) 4 to 7. Wound care assessments began on HD10; wounds to low back and bilateral buttocks were noted. By HD15, O2 requirements were further weaned and Patient was transferred to Acute Inpatient Rehab. On Rehab admission, Patient had Leukocytosis and wounds noted as “Unstageable”. Antibiotic coverage was increased (Cefepime). By HD28/ Rehab Day (RD) 13, wound culture was positive, and antibiotic regimen was further supplemented (Metronidazole, Fluconazole, Daptomycin). MRI thoracic spine and pelvis demonstrated “necrotizing soft-tissue infection”. Surgical debridement occurred HD31/RD16 with subsequent anemia, requiring transfusion. She underwent additional surgical debridement on HD38/RD23 and was returned to the Acute floors. She was discharged to home with outpatient wound care on HD53. Main Outcome Measures Wound size (area). Results Wound size: Hospital Day (HD) 10: 284.39cm2; HD16/Rehab Day (RD) 1: 698.6cm2; HD34/RD19: 265.66; HD39:747.72cm2; HD51: Area = 992.80cm2. ∆Area, Pre-Rehab (HD16-HD10): (+) 414.2cm2; ∆Area, Rehab (HD34/RD19-HD16/RD1): (-) 439.94; ∆Area, Post-Rehab (HD51-HD34): (+) 727.14. Conclusions Inpatient Rehabilitation practices may help ameliorate pressure injury in cases of VDRF secondary to COVID-19 infection. Further study is warranted on the potential integration of such practices in this patient population, as a preventative measure in the Acute and/or Critical care settings. Author(s) Disclosures Affiliation: HCA Healthcare (MountainView Hospital) Disclaimer: This research was supported (in whole or in part) by HCA Healthcare and/or an HCA Healthcare affiliated entity. The views expressed in this publication represent those of the authors and do not necessarily represent the official views of HCA Healthcare or any of its affiliated entities. | Arch Phys Med Rehabil | 2022 | CORD-19 | |
| 5540 | Impact of COVID-19 on Frailty, Sarcopenia and Functionality After Hospital Discharge Research Objectives To evaluate the impact of covid-19 on frailty, sarcopenia and patient functionality after hospital discharge. Design This is a prospective cohort study. The patients will monitor after hospital discharge by COVID-19 for one year with evaluations at one, four, six and twelve months after hospital discharge. Setting This study was carried out in a reference Hospital for the treatment of COVID19 in São Paulo / Brazil. Participants This study evaluated 68 patients, both genders, 18 years old or more that needed to receive treatment for COVID-19 in the hospital. Interventions This is a prospective cohort study with only apply assessment instruments in different periods. Main Outcome Measures Patients were contacted by telephone and answered a questionnaire regarding sociodemographic data and the scale Barthel index, SARC-F and Clinical Frailty Scale (CFS) in relation to their condition before COVID-19, after 1 month and 4 months of hospital discharge. Results 68 patients, mean age of 60.2 (±11.3) years, 35 (51.4%) males, were evaluated. Before COVID-19, 8 (11.7%) patients used an auxiliary gait device, 4 (5.8%) were wheelchair users, 44 (64.7%) were independent (Barthel index=100) and 24 (35.2%) had impairment in at least one daily living activity (Barthel index <95). Barthel index score (p <.001), Sarc-F (p <.001) and CFS (p <.001) worse after 1 month of the hospital discharge. In addition, after 1 month of the hospital discharge, there was a worsening of Barthel index (p < 0.001), Sarc-F (p < 0.001), and CFS (p < 0.001). Finally, after 4 months of hospital discharge Sarc-F and CFS did not improve compared to the period before covid-19. Conclusions It is concluded that after hospitalization for COVID-19 there is a decrease in functionality and worsening of the conditions of sarcopenia and frailty. Despite functionality returning to baseline after 4 months, sarcopenia and frailty remained deficient when compared to the pre-hospitalization period. Therefore, a long-term follow-up is necessary for evaluation and rehabilitation after hospitalization by COVID-19 Author(s) Disclosures There is no conflict of interest on the part of the authors. | Arch Phys Med Rehabil | 2022 | CORD-19 | |
| 5541 | Hallucinations in Hospitalized Rehabilitation Patients with COVID-19 Research Objectives To describe the characteristics of hallucinations in hospitalized rehabilitation patients with coronavirus disease 2019 (COVID-19). Design An observation study of case series. Setting Acute inpatient rehabilitation public hospital. Participants Patients with COVID-19 who were admitted to the acute inpatient rehabilitation unit (ARU) during a four-month period. Interventions Not applicable. Main Outcome Measures To describe the characteristics of hallucinations in hospitalized rehabilitation patients with COVID-19. Results Eight (21.6%) of a cohort of 37 patients admitted to the ARU with COVID-19 exhibited visual hallucinations. Most of the visual hallucinations occurred during their ICU stay. The mean age of the eight patients was 56.5-year-old (range: 38 – 71). There were seven males and one female. Seven of the eight patients exhibited peduncular hallucinations, four were associated with auditory components, five with tactile components. One patient's hallucinations were characterized by a duplication of an extra finger, an enlargement of an upper extremity, a tactile hallucination of crawling bugs, and a somatic component of abnormal positioning of an extremity. The content of the hallucinations was related to the fearful and threatening situations in three patients and the experience of seeing deceased family members in two patients. Five of the patients had ICU delirium. Seven patients had COVID-19 pneumonia and one patient developed respiratory distress secondary to Guillain-Barre Syndrome. One patient experienced posterior reversible encephalopathy syndrome which was associated with visual hallucinations. Four patients had anxiety, four had depression, and one had both anxiety and depression. None had a pre-existing history of psychiatric illness, but one had a pre-existing history of methamphetamine use. All eight patients had evidence of cognitive impairment. Hallucinations of six patients resolved spontaneously but those of two patients had persisted during their ARU stay. The negative experience of hallucinations warranted further multidisciplinary support during their recovery. Conclusions Visual hallucinations can be encountered among hospitalized patients with COVID-19. It is uncertain whether these hallucinations were directly or indirectly related to the SARS-CoV-2 infection. Author(s) Disclosures No conflict to declare in all authors. | Arch Phys Med Rehabil | 2022 | CORD-19 | |
| 5542 | Appraisal of Long COVID: Lessons to be Learned from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Objective(s) Little is known regarding after-effects of Long-COVID-19 (LC), while ME/CFS has been extensively researched. We performed a rigorous scoping review to inform a better definition of symptomatology of LC and cross-cutting similarities with ME/CFS. Our objective was to review the National Institutes of Health (NIH) ME/CFS Common Data Elements (CDEs), identify Patient Reported Outcome Measures (PROMs) and link items to the World Health Organization (WHO) International Classification of Functioning, Disability and Health (ICF) codes to inform efforts to define LC. Data Sources NIH ME/CFS CDEs (Jan. 2020), Google Scholar, PubMed - search terms: Long COVID and ME/CFS. Study Selection A review of 119 NIH ME/CFS CDEs applied the following inclusion criteria: 1) PROM based; 2) assess symptomatology; 3) specific to adults 18 years and over; 4) no visual or pictographic scales. Data Extraction Of the 119 NIH ME/CFS CDEs, 38 met review criteria; items were entered into an Excel spreadsheet. Five researchers independently coded items using ICF linking rules and resolved discrepancies using a consensus-based process. Data Synthesis Six articles specifically compared LC and ME/CFS for symptom overlap. Similarities between ME/CFS and Long COVID symptoms include: fatigue, post exertional malaise (PEM), cognitive symptoms, sleep dysfunction, pain, noise and light hypersensitivity, orthostatic intolerance, cardiac, gastrointestinal and immune pathologies. The 944 items from 38 PROM CDEs were coded based on common ME/CFS and LC symptoms. The percent of items linked to one or more ICF categories (1288 codes) was as follows: Body Function (b codes) 73%: Fatigability, N=252 (20%); Cognitive functions, N=234 (18%); Sleep functions, N=139, 11%; and Pain, N=119, (9%). Activity and Participation (d codes), N=332, (26%). Environment (e codes), N=11, 0.9%. Conclusions The ICF provides a common language to assess ME/CFS and LC cross-cutting symptoms and their impact on body function, activity and participation. This review of ME/CFS CDE's can help identify common symptoms, such as PEM, and encourage appropriate symptom management to prevent cycles of overexertion and relapse for those with LC. Author(s) Disclosures The authors have no conflicts of interest to declare. | Arch Phys Med Rehabil | 2022 | CORD-19 | |
| 5543 | A Retrospective Study of Post-COVID Recovery Clinic's Screening Data to Determine Prevalence of Frailty And Pre-Frailty Among COVID-19 Survivors Research Objectives To determine the prevalence of pre-frailty and frailty among COVID-19 survivors treated at a hospital system-based Post-COVID Recovery Clinic. Design Retrospective study using Post-COVID Recovery Clinic screening data. Setting A hospital system-based Post-COVID Recovery Clinic. Participants COVID-19 survivors ≥18 years old (n=287) seen at a Post-COVID Recovery Clinic between July 2020 to May 2021. Interventions Descriptive statistics were used to describe demographics and patient-reported information. Differences in frailty status by demographics and patient-reported information were assessed with Chi-square test and analysis of variance. Main Outcome Measures Frailty and pre-frail status were determined based on five pre-defined criteria described by Fried and colleagues. Our modified criteria were drawn from clinic screening questions on significant weight loss, exhaustion, activity level, walking difficulty as a surrogate measure of walking speed, and ability to open jars or grip and open things. Results COVID-19 survivors (Mage 52.6 ± 14.8 years old, 64.5% female) had ≥ 1 comorbidity, average of 70.82 ± 60 days from COVID diagnosis to follow-up, 6±4 symptoms at the clinic visit, and 2.79±1.06 special care referrals. Of those previously hospitalized, the average length of stay was 7.28 ± 7.89 days. About 53.1% of COVID-19 survivors were pre-frail, and 30.0% were frail. The age group with the highest proportion of frailty was 40-65 years (61%), followed by ages 65+ (23.2%) and 18-39 (15.9%). Conclusions Our preliminary results indicate that about 1 in 3 COVID-19 survivors met frailty criteria with the majority in the middle age range. Most experienced multiple symptoms 3 months post-diagnosis and needed an average of 3 referrals. Our results warrant further investigation and may indicate targeted interventions to prevent development of permanent disability among COVID-19 survivors. Author(s) Disclosures None. | Arch Phys Med Rehabil | 2022 | CORD-19 | |
| 5544 | The Impact of the COVID-19 Pandemic on Aspects of Health Among Community Dwelling Survivors of a Moderate-Severe Traumatic Brain Injury (TBI) Research Objectives To understand the impact of the COVID-19 pandemic on aspects of health and lifestyle behaviors among community dwelling survivors of a traumatic brain injury (TBI). Design Cross-sectional, descriptive study. Setting Community-based. Participants N = 28 community dwelling survivors of moderate/severe TBI and were at least one year up to 5-years post-injury (M age = 40.59; SD=18.61) and part of an ongoing study. Interventions N/A. Main Outcome Measures A checklist of comprehensive health/lifestyle areas. Participants were asked think about their experiences over the past year since the COVID-19 breakout and to indicate if the COVID-19 pandemic impacted various areas of health and lifestyle (yes/no). If they endorsed “yes”, they were then asked to indicate if the impact was for the better or worse for each endorsed area. They were then asked to elaborate on their response (qualitative data). Results All health areas were impacted by the pandemic. The most frequently impacted area was social relationships (64.3%) followed by leisure (53%), physical activity (46.4%), mental health (25%), mental activity (25%), stress management (21.4%), spirituality/purpose and meaning (21.4%), alcohol use (21.4%) and to a lesser extent tobacco use (17.9%), health knowledge/information (10.7%), nutrition (7.1%), and sleep (3.6%). Of those who endorsed being impacted by the pandemic, the following frequencies indicate health areas that worsened due to the pandemic: 92.3% for physical activity, 83.3% stress management, 83.3% social relationships, 83.3% spirituality/purpose and meaning, 71.4%, mental health, 66.7 % leisure, 66.7% tobacco use, 53.6% leisure, 50% alcohol use, and 25% mental activity. Areas that were reported “better” were 100% for nutrition and dietary intake, 100% for health knowledge/information, and 100% sleep. Conclusions The pandemic negatively impact numerous health areas among community dwelling survivors of a TBI. Addressing the impact of the COVID-19 pandemic on health areas along with taking into consideration the likely disruptions in healthcare will help identify survivors who may benefit from health promotion interventions to prevent or intervene on secondary health conditions. Author(s) Disclosures No conflicts of interest. | Arch Phys Med Rehabil | 2022 | CORD-19 | |
| 5545 | Impact of the COVID-19 Pandemic on Employment of People with Disabilities and Employers Research Objectives This research aimed to describe how the COVID-19 pandemic affected the work status of people with disabilities (PWD) and employers involved in hiring and managing of PWD. Design Two cross-sectional surveys. Setting PWD and employers involved in hiring and managing PWD, primarily in the Midwestern United States. Participants Convenience sample of 733 PWD and 67 employers recruited through multiple sources. Interventions None. Main Outcome Measures Employment consequences of the COVID-19 pandemic as experienced by PWD and employers. Results Among survey respondents with disabilities, 25% reported employment changes during the pandemic. Among participants reporting changes, 48% were not working, and 16% lost their jobs due to business reductions. For PWD who maintained employment, 67% reported that their work was moderately or greatly affected by the COVID-19 pandemic. PWD reported decreased pay or financial problems (42%) resulting from furloughs, leaves, or reduced work hours (40%), working remotely more than usual (41%), and experiencing a harder time getting their work done (23%). In contrast, nearly all employers (97%) reported being affected by the COVID-19 pandemic. Changes included switching to virtual operations (69%), temporarily closing a business (26%), furloughing employees (25%), and laying off employees (23%). Primary reasons for business changes included concerns about the spread of COVID-19, adherence to government policies, and difficulty providing services during the pandemic. Conclusions The COVID-19 pandemic adversely affected employment of PWD as reported by workers and employers. Findings parallel the experience of the nondisabled workforce, but reveal vulnerabilities that reflect disability consequences and the need for job accommodations. Flexible work hours and opportunities to work remotely benefit PWD in particular. Policy implications reflect the benefits of flexible working hours and locations. Author(s) Disclosures The authors report no conflicts of interest. | Arch Phys Med Rehabil | 2022 | CORD-19 | |
| 5546 | Six Minute Walk Test Changes during Long-Term Acute Care Hospital Rehabilitation for Patients post-COVID-19 Research Objectives To explore Six Minute Walk Test (6MWT) improvements in patients admitted to long-term acute care hospitals (LTACHs) for severe and prolonged SARS-Cov-2 illness (COVID-19). Design National retrospective longitudinal cohort. Setting Five LTACHs in USA. Participants 184 (77.3% of 238 total) participants post-COVID-19 [mean age 64.5 (13.1) years] for whom 6MWT scores were available at admission and discharge. Interventions Participants received standard inpatient LTACH care. 6MWT distance measured using established procedures. Main Outcome Measures 6MWT distance change. We defined improvement as 54m, which is the minimal clinically important difference (MCID) identified for individuals with pulmonary diseases . Results Prior to LTACH transfer, participants’ average hospitalization length of stay was 30.9 days (SD=20.1), with 85% staying in an ICU for ≥3 days, 58% diagnosed with acute respiratory distress syndrome, 65% receiving mechanical ventilation, and 30% having tracheostomies. During LTACH stay, average 6MWT distance increased from admission [median 0m (IQR 0-0)] to discharge [median 13.4m (IQR, 0-82)], with 32% of participants exceeding the MCID. The discharge average 6MWT distance for those who improved was 180.9m (SD=112.5; range=61-592) versus 10.1m (SD=17.8; range=0-95.7) for those without improvement. Patients who improved were younger (60.8 vs. 66.3 years; p=0.01), ventilated for less time (18.7 vs 26.9 days; p=0.004) and were less likely to have a tracheostomy (15.5% vs 37.9%; p=0.002). Conclusions Among a national cohort of patients with the most severe and prolonged COVID-19 illness, nearly one-third had improved 6MWT distance exceeding established MCID thresholds. Short distances traversed by those not exceeding the MCID confirm persisting mobility dysfunction expected to hinder community participation. Even for those exceeding the MCID threshold, many did not achieve the 6MWT distance threshold of 205m previously identified as discriminating between home and community ambulators. Collectively, findings highlight the need for further research to identify strategies (medical, therapeutic) to enhance walking during rehabilitation and post discharge for patients cared for in LTACH settings following hospitalization for COVID-19. Author(s) Disclosures Research supported by grants from NALTH and the National Institute on Aging (PI: Makam). | Arch Phys Med Rehabil | 2022 | CORD-19 | |
| 5547 | Spaulding REhabilitation and COVid Recovery study (RECOVR): Preliminary Findings at 6 Months Research Objectives To identify distinct post-acute COVID-19 phenotypes among adults hospitalized for severe SARS-CoV-2 infection and describe multidimensional outcomes at 6 months post-hospitalization. Design Prospective, longitudinal data collection in functional, physical, cognitive, and psychological domains at 3, 6, and 12 months post-hospitalization. Retrospective data collection from the acute care and post-acute care settings. Setting Acute care and post-acute telephone follow-up. Participants Spanish- and English-speaking adults, with decision-making capacity, admitted for inpatient rehabilitation following inpatient hospitalization for acute COVID-19 related illness (N = 52). Interventions N/A. Main Outcome Measures Physical, cognitive, and psychological symptoms; Self-reported employment status and assistance with ADLs. Results Median age was 60.96 (IQR = 20.89), with race/ethnicity representative of the US adult population (71% White; 13% Black; 27% Hispanic). Compared to premorbid status, 33% of individuals were no longer employed full-time and 23% were no longer independent in basic ADLs. Latent profile analysis identified distinct subgroups within physical, cognitive, and emotional domains of functioning. Approximately 31% were in either the moderately or most symptomatic groups for both cognitive and emotional functioning, with 88% of these also falling into the most symptomatic group for physical functioning. There were 29% in the least symptomatic group across all domains. Conclusions Persons with severe COVID-19 illness experience persistent functional limitations that interfere with employment and ADLs up to 6 months post-hospitalization. Although symptom variability is high at 6 months, we identified distinct subgroups, including those with co-occurring emotional and cognitive symptoms, that suggest the need for comprehensive assessment and tailored treatment for physical, emotional, and cognitive symptoms. Author(s) Disclosures The author's declare no relevant conflict of interests. | Arch Phys Med Rehabil | 2022 | CORD-19 | |
| 5548 | Heterotopic Ossification in Post-COVID-19 Patient on Anticoagulation with Limited Treatment Options Research Objectives To investigate treatment options for heterotopic ossification in the setting of COVID-19 and anticoagulation use. Design Case report. Patient followed through the entirety of inpatient acute rehabilitation. Used chart review to examine events during his intubation before coming to rehab. Setting University affiliated Acute Rehabilitation Unit. Participants Case report: 59-year-old male with a past medical history of diabetes, hypertension, and pulmonary embolism on anticoagulation who developed heterotopic ossification (HO) after a prolonged hospitalization secondary to COVID-19. He presented to the ED with dyspnea and was noted to have bilateral pleural effusion and +SARS-CoV-2. He was admitted for COVID-19 treatment and was subsequently intubated. While intubated, he received Physical Therapy (PT) and was noted to have progressive hip pain by day 23 that interfered with PT. A CT of his abdomen and pelvis was done on day 30 of his intubation without any significant bony abnormalities. He was subsequently extubated after 43 days, stabilized, and admitted to acute rehabilitation for ICU associated weakness 15 days later. He continued to have worsening hip pain. Bilateral hip radiographs and follow up CT hips were obtained on rehabilitation day 35 (day 103 of overall hospitalization), which demonstrated Booker Grade 3 HO on the right and Booker Grade 2 on the left. Interventions A multidisciplinary approach to treatment was sought using consultants from Orthopedics, Endocrinology, Radiation Oncology, Pharmacy, and PT. Due to his anticoagulation and high risk factors, nonsteroidal anti-inflammatory drugs were not recommended. Radiation therapy and bisphosphonates were also not recommended. His pain was controlled with acetaminophen as needed and tizanidine which allowed him to participate in therapies during his rehabilitation admission. Main Outcome Measures Radiologic images and clinical description or pain/pain control. Results Utilized a multidisciplinary approach. Care included NSAID avoidance, acetaminophen as needed, tizanidine, and PT which provided pain control without compromising coagulation status in the setting of COVID-19. Conclusions HO is a known complication in COVID-19 patients requiring extended intubation which presents unique treatment challenges related to this diagnosis. Author(s) Disclosures No disclosures. | Arch Phys Med Rehabil | 2022 | CORD-19 | |
| 5549 | Verbal Working Memory Decline After COVID-19 in 20s Research Objectives To investigate the impact of the COVID-19 on the performance in verbal working memory in 20s. Design Between Subjects design. Setting Research Lab in the Department of Communication Sciences & Disorders at the Baylor University. Participants Total 29 young participants in 20s with and without the history of the COVID-19 participated in this study virtually: 1) Non-COVID group: N=19, Age=21.53, SD=1.17, Education=16.29, SD=1.06, and 2) COVID group: N=10, Age=21, SD=1.41, Education=15.8, SD=1.16. Interventions N/A. Main Outcome Measures Composite verbal working memory scores (from Alphabet Span Task and Subtract-2 Span Task) were calculated for an outcome measure and compared between the COVID and Non-COVID groups. Results There was a statistically significant difference between groups as determined by one-way ANOVA (F(1,27) = 5.086, p = .032). The verbal working memory performance was statistically significantly lower in the COVID group (15.8 ± 2.8) compared to the Non-COVID group (18.18 ± 2.66). Conclusions The results revealed that the COVID group's verbal working memory performance was statistically significantly lower than the Non-COVID group's performance. The results indicate that the history of the COVID-19 may negatively affect the performance of the verbal working memory in 20s. Author(s) Disclosures The author's salary has been funded by the University. | Arch Phys Med Rehabil | 2022 | CORD-19 | |
| 5550 | N/A | N/A | 0000 | CORD-19 |
(1) COVID-19 Open Research Dataset (CORD-19). 2020. Version 2022-06-02. Retrieved from https://ai2-semanticscholar-cord-19.s3-us-west-2.amazonaws.com/historical_releases.html. Accessed 2022-06-05. doi:10.5281/zenodo.3715506
(2) Chen Q, Allot A, & Lu Z. (2020) Keep up with the latest coronavirus research, Nature 579:193 and Chen Q, Allot A, Lu Z. LitCovid: an open database of COVID-19 literature. Nucleic Acids Research. 2020. (version 2023-01-10)
(3) Currently tweets of June 23rd to June 29th 2022 have been considered.